Medical Science Liaison - Southeast
RemoteMedical Affairs – Medical Affairs /Regular, Full-Time Employee /Remote
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More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Position Summary:
The MSL reports to the Sr. Director, National Field Medical Affairs and will be responsible for fostering strong relationships with key opinion leaders (KOLs) and supporting the scientific and clinical strategy of Orca Bio's next generation allogeneic cell therapies. The ideal candidate will possess deep expertise in hematopoietic stem cell transplantation (HSCT), cellular therapy, and the evolving cell therapy landscape, including clinical, operational, regulatory and market access considerations. The MSL will serve as trusted scientific partner between Orca Bio and external healthcare providers (HCPs) establishing strong professional collaborations with investigators and other HCPs within the designated territory. Additionally, you will serve as an active leader and contributor on projects in support of the Medical Affairs Strategic Objectives.
Candidate must reside in Florida, South Carolina, Georgia, Alabama, Mississippi, Louisiana, or Arkansas.
Responsibilities
Serve as a subject matter expert in stem cell transplantation, cell therapy, and the evolving cellular immunotherapy landscape, providing scientific insights regarding current treatment paradigms, clinical operations, patient access and emerging competitive landscape
Identify, develop, and maintain deep scientific, peer-to-peer relationships with academic stem cell therapy experts as well as thought leaders, appropriate HCPs, and access stakeholders, within a given geography to answer scientific and product related questions, to ensure their safe and appropriate use of Orca Bio products through peer-to-peer discussions aligned with medical strategies and needs expressed by external stakeholders
Prepare and maintain a territory management plan that will be shared with Medical Leadership and other internal stakeholders
Engage with Orca “Pod” field team members to provide appropriate medical support for all onboarding activities in relation to authorizing treatment centers, adverse event reporting, handling out of spec products, as well as partnering with regional Market Access colleagues to provide medical education and support to local payers in alignment with Market Access tactical plan and individual patient needs
Develop and maintain a deep and current understanding of hematologic malignancies, stem cell transplantation, cell therapy, cellular immunotherapy and competitive developments to facilitate high level scientific exchange with health care professional and key opinion leaders
Actively assess the transplant and cell therapy landscape through ongoing engagement with key opinion leaders, investigators, and academic research centers to identify emerging scientific trends, evidence gaps, and novel research opportunities relevant to Orca Bio's therapies. Serve as the primary liaison for Orca Bio's Investigator-Sponsored Trial (IST) program, partnering with investigators to develop and refine research concepts, evaluate scientific merit and strategic alignment, support proposal and protocol development, present qualified concepts to review committees, communicate governance decisions, and provide scientific oversight throughout study start-up, conduct, publication planning, and dissemination of results
Gather and communicate actionable scientific insights and stakeholder feedback to Orca Bio leadership and cross-functional partners to inform medical strategy, evidence generation priorities, and lifecycle planning
Provide scientific and clinical expertise to support internal and external stakeholders, through participation in advisory board meetings, clinical investigator meetings, roundtable discussions, educational meetings, interactions with professional organizations/societies, advocacy groups, GPOs, and large networked practices as needed, including speaker bureaus
Support clinical trial activities to enhance patient recruitment, enrollment and/or discussions around the safe and effective use of Orca Bio investigational products, leveraging clinical trial experience and knowledge of Good Clinical Practice (GCP) to ensure adherence to ethical and regulatory standards
Lead the collection, analysis, synthesis and dissemination of scientific information presented at congresses and during scientific exchange. Translate emerging clinical trial data, competitive intelligence and external stakeholder feedback into actional recommendations for Orca Bio leadership and cross functional teams. When assigned, coordinate the efforts of other MSLs to provide coverage for a specific congress to maximize organizational impact
Provide medical and scientific support of the strategy of health outcomes, real-world evidence, and payer/provider engagements
Initiate and autonomously execute projects that align with Orca Bio’s scientific, clinical and business operations partnering with research, clinical development, commercial, market access, regulatory, and quality functions to drive company strategy
Provide education and training to commercial marketing and sales teams on therapies and disease states
Required Qualifications
Advanced clinical degree in a life-science or basic-science discipline (MD, DO, PharmD, NP, PA, DNP, M.Sc, or Ph.D.) and industry experience as an MSL
Significant clinical and/or industry experience in malignant hematology, hematopoietic stem cell transplant (HSCT), cellular therapy, CAR-T, immune effector cell therapies, and/or other advanced therapy modalities
Strong understanding of cell therapy ecosystem, including transplant center operations, apheresis and cell processing workflows, treatment center authorization, patient referral pathways and competitive cell therapy products
Strong understanding of clinical development, regulatory requirements, and commercial strategies; experience with HEOR data is a plus
Excellent interpersonal and communication skills, with the ability to engage and influence a wide range of stakeholders
Demonstrated ability to interpret and present complex scientific data to diverse audiences
Strong strategic thinking, problem-solving skills, and solution-oriented mindset
Demonstrated ability to collaborate with cross-functional colleagues to best serve the needs of internal and external stakeholders
Ability to work independently and manage multiple priorities in a fast-paced, dynamic environment
Preferred Experience
5+ years of industry experience as an MSL
Demonstrated experience with field medical launch planning, execution, and post-launch support
Direct experience supporting cell therapy, stem cell transplantation, CAR-T or other advanced therapeutic platforms
Experience working in a small biotech company or start-up environment
$195,000 - $245,000 a year
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
Who we are
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
Notice to staffing firms
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
APPLY FOR THIS JOB
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Listed by Orca Bio for a position based in the United States. Employers on this board attest they are hiring domestically.
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Position Summary:
The MSL reports to the Sr. Director, National Field Medical Affairs and will be responsible for fostering strong relationships with key opinion leaders (KOLs) and supporting the scientific and clinical strategy of Orca Bio's next generation allogeneic cell therapies. The ideal candidate will possess deep expertise in hematopoietic stem cell transplantation (HSCT), cellular therapy, and the evolving cell therapy landscape, including clinical, operational, regulatory and market access considerations. The MSL will serve as trusted scientific partner between Orca Bio and external healthcare providers (HCPs) establishing strong professional collaborations with investigators and other HCPs within the designated territory. Additionally, you will serve as an active leader and contributor on projects in support of the Medical Affairs Strategic Objectives.
Candidate must reside in Southern California, Arizona, New Mexico, or Colorado.
\n
Responsibilities
Serve as a subject matter expert in stem cell transplantation, cell therapy, and the evolving cellular immunotherapy landscape, providing scientific insights regarding current treatment paradigms, clinical operations, patient access and emerging competitive landscape
Identify, develop, and maintain deep scientific, peer-to-peer relationships with academic stem cell therapy experts as well as thought leaders, appropriate HCPs, and access stakeholders, within a given geography to answer scientific and product related questions, to ensure their safe and appropriate use of Orca Bio products through peer-to-peer discussions aligned with medical strategies and needs expressed by external stakeholders
Prepare and maintain a territory management plan that will be shared with Medical Leadership and other internal stakeholders
Engage with Orca “Pod” field team members to provide appropriate medical support for all onboarding activities in relation to authorizing treatment centers, adverse event reporting, handling out of spec products, as well as partnering with regional Market Access colleagues to provide medical education and support to local payers in alignment with Market Access tactical plan and individual patient needs
Develop and maintain a deep and current understanding of hematologic malignancies, stem cell transplantation, cell therapy, cellular immunotherapy and competitive developments to facilitate high level scientific exchange with health care professional and key opinion leaders
Actively assess the transplant and cell therapy landscape through ongoing engagement with key opinion leaders, investigators, and academic research centers to identify emerging scientific trends, evidence gaps, and novel research opportunities relevant to Orca Bio's therapies. Serve as the primary liaison for Orca Bio's Investigator-Sponsored Trial (IST) program, partnering with investigators to develop and refine research concepts, evaluate scientific merit and strategic alignment, support proposal and protocol development, present qualified concepts to review committees, communicate governance decisions, and provide scientific oversight throughout study start-up, conduct, publication planning, and dissemination of results
Gather and communicate actionable scientific insights and stakeholder feedback to Orca Bio leadership and cross-functional partners to inform medical strategy, evidence generation priorities, and lifecycle planning
Provide scientific and clinical expertise to support internal and external stakeholders, through participation in advisory board meetings, clinical investigator meetings, roundtable discussions, educational meetings, interactions with professional organizations/societies, advocacy groups, GPOs, and large networked practices as needed, including speaker bureaus
Support clinical trial activities to enhance patient recruitment, enrollment and/or discussions around the safe and effective use of Orca Bio investigational products, leveraging clinical trial experience and knowledge of Good Clinical Practice (GCP) to ensure adherence to ethical and regulatory standards
Lead the collection, analysis, synthesis and dissemination of scientific information presented at congresses and during scientific exchange. Translate emerging clinical trial data, competitive intelligence and external stakeholder feedback into actional recommendations for Orca Bio leadership and cross functional teams. When assigned, coordinate the efforts of other MSLs to provide coverage for a specific congress to maximize organizational impact
Provide medical and scientific support of the strategy of health outcomes, real-world evidence, and payer/provider engagements
Initiate and autonomously execute projects that align with Orca Bio’s scientific, clinical and business operations partnering with research, clinical development, commercial, market access, regulatory, and quality functions to drive company strategy
Provide education and training to commercial marketing and sales teams on therapies and disease states
Required Qualifications
Advanced clinical degree in a life-science or basic-science discipline (MD, DO, PharmD, NP, PA, DNP, M.Sc, or Ph.D.) and industry experience as an MSL
Significant clinical and/or industry experience in malignant hematology, hematopoietic stem cell transplant (HSCT), cellular therapy, CAR-T, immune effector cell therapies, and/or other advanced therapy modalities
Strong understanding of cell therapy ecosystem, including transplant center operations, apheresis and cell processing workflows, treatment center authorization, patient referral pathways and competitive cell therapy products
Strong understanding of clinical development, regulatory requirements, and commercial strategies; experience with HEOR data is a plus
Excellent interpersonal and communication skills, with the ability to engage and influence a wide range of stakeholders
Demonstrated ability to interpret and present complex scientific data to diverse audiences
Strong strategic thinking, problem-solving skills, and solution-oriented mindset
Demonstrated ability to collaborate with cross-functional colleagues to best serve the needs of internal and external stakeholders
Ability to work independently and manage multiple priorities in a fast-paced, dynamic environment
Preferred Experience
5+ years of industry experience as an MSL
Demonstrated experience with field medical launch planning, execution, and post-launch support
Direct experience supporting cell therapy, stem cell transplantation, CAR-T or other advanced therapeutic platforms
Experience working in a small biotech company or start-up environment
\n
$195,000 - $245,000 a year
\n
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
Who we are
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
Notice to staffing firms
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.
Listed by Orca Bio for a position based in the United States. Employers on this board attest they are hiring domestically.
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Position Summary:
The MSL reports to the Sr. Director, National Field Medical Affairs and will be responsible for fostering strong relationships with key opinion leaders (KOLs) and supporting the scientific and clinical strategy of Orca Bio's next generation allogeneic cell therapies. The ideal candidate will possess deep expertise in hematopoietic stem cell transplantation (HSCT), cellular therapy, and the evolving cell therapy landscape, including clinical, operational, regulatory and market access considerations. The MSL will serve as trusted scientific partner between Orca Bio and external healthcare providers (HCPs) establishing strong professional collaborations with investigators and other HCPs within the designated territory. Additionally, you will serve as an active leader and contributor on projects in support of the Medical Affairs Strategic Objectives.
Candidate must reside in Southern California, Arizona, New Mexico, or Colorado.
Listed by Orca Bio for a position based in the United States. Employers on this board attest they are hiring domestically.
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Position Summary:
The MSL reports to the Sr. Director, National Field Medical Affairs and will be responsible for fostering strong relationships with key opinion leaders (KOLs) and supporting the scientific and clinical strategy of Orca Bio's next generation allogeneic cell therapies. The ideal candidate will possess deep expertise in hematopoietic stem cell transplantation (HSCT), cellular therapy, and the evolving cell therapy landscape, including clinical, operational, regulatory and market access considerations. The MSL will serve as trusted scientific partner between Orca Bio and external healthcare providers (HCPs) establishing strong professional collaborations with investigators and other HCPs within the designated territory. Additionally, you will serve as an active leader and contributor on projects in support of the Medical Affairs Strategic Objectives.
Candidate must reside in Florida, South Carolina, Georgia, Alabama, Mississippi, Louisiana, or Arkansas.
Listed by Orca Bio for a position based in the United States. Employers on this board attest they are hiring domestically.
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Senior Manager, Projects and Programs - Research
South San Francisco, California, United States
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About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
About the Role
We are seeking a Project Manager to support Xaira’s high-priority Agentic AI Initiatives, including X-Cell, X-Design, and related programs. This role is well suited for a candidate with a strong scientific and software background who has experience with cross-functional project management in research settings, where ML/AI system and biologics R&D intersect. The ideal candidate will have hands-on experience with ML model training and evaluation, agentic AI systems (tool use, orchestration, human in the loop review), software development, and biologics R&D, with the ability to manage timelines, track deliverables, and partner closely with scientific and technical leads to keep fast-moving programs on track.
This position emphasizes scientific and technical depth, coordination across ML, engineering, and scientific teams, and milestone tracking in an environment where playbooks are being defined and evolving rapidly. It is a strong fit for someone with a technical background at the interface of ML, software, and biology who is comfortable managing cross-functional projects and collections of project driving towards program objectives and milestones.
Key Responsibilities
Project Planning and Execution
Support day-to-day planning and coordination of platform research programs, ensuring clear communication of next steps, expected deadlines, and needs to stakeholders.
Build and maintain project timelines that capture critical milestones, dependencies, and deliverables.
Partner with scientific leads and functional stakeholders to align on scope, priorities, and progress.
Milestone Management & Decision Support
Collaborate with scientific teams to define key project milestones, decisional experiments and translate into actionable, resource-information timelines.
Help compile project data, timelines, risks, and trade-offs to support informed decision- making.
Coordinate and facilitate planning and documentation of decisive experiments, and update project plans based on results and next steps.
Cross-Functional Project Coordination
Facilitate cross-functional collaboration across research to ensure effective communication and documentation of decisions, alignment of priorities and timelines.
Schedule and run cross-functional meetings, ensuring clear agendas, effective documentation, and follow-up on action items.
Monitor interdependencies across functions and proactively identify, flag and resolve conflicts across workstreams.
Operational Support & Project Monitoring
Track project status, risks, and mitigation strategies; provide updates to internal stakeholders.
Coordinate with functional leads to understand resource needs and potential impacts to timelines.
Contribute to scenario planning and contingency thinking for critical path activities
Identify operational challenges and recommend improvements to enhance efficiency and coordination.
Resource Coordination & Timeline Scenarios
Work closely with functional and team leads to understand resourcing needs, identify gaps and timeline impacts.
Develop scenario plans for critical path development decisions to support contingency and investment planning to address potential delays, bottlenecks, or shifts in scope.
Qualifications
Advanced degree (MS, PhD, or equivalent) in life sciences, bioinformatics, computational biology or a related field strongly preferred.
Minimum of 6+ years of industry experience, including hands-on biologics research with demonstrated project or timeline management responsibilities.
Proven track record of managing research and/or technical programs
Working fluency in biologics research and ML research with hands on experience a big plus.
Strong analytical, planning, and organizational skills; able to translate complex scientific ideas into clear plans.
Excellent communication, time management collaboration, and stakeholder management skills.
Experience with basic project tracking tools (Excel, Smartsheet, MS Project, Asana, Google Suite, etc).
Working familiarity with project and program management principles as defined by the Program Management Institute (PMI) or similar bodies. PMP, CAPM, or PMI-ACP certifications are a plus, but note hands on experience matters more than the credential itself.
Please note that this position will be required to be on-site in the SSF office.
Preferred Attributes
Comfortable managing projects in a fast-paced, cross-functional environment.
Hands-on experience both with wet-lab and computational research. Experience with data generation for training large machine learning models in biology would be greatly preferred.
Demonstrated ability to lead and influence diverse teams, both functionally and at different levels of seniority.
Passion for science and dedication to improving patient outcomes through innovative biologics development.
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $148,000 - $185,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
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Listed by Xaira Therapeutics for a position based in the United States. Employers on this board attest they are hiring domestically.