Jobs - Jobs4Americans

ABOUT CHAI DISCOVERY Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets that other methods cannot reach. AI is reinventing life sciences the same way it reinvented software engineering, and Chai is at the forefront of this shift. Leading pharmaceutical companies like Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, and Novartis https://www.chaidiscovery.com/news/novartis-partnership are rapidly adopting our platform to power their drug discovery programs. Our mission is to accelerate progress towards new cures and better science, and there are countless interesting problems on the road ahead. About the role Security is what earns Chai the trust of the world's largest pharma companies. It's a precondition for the business. We're looking for someone to drive and build the security function end to end. You'll represent Chai's security posture to our partners, sitting across from their CISOs and cloud security architects on reviews of our compute architecture, tenant isolation, egress controls, encryption, and key management. You'll drive the changes they surface back into our platform and infrastructure, keeping Chai ahead of new risks. Just as importantly, you'll be the trusted security partner to our product and platform engineers, reviewing systems like our shared inference fleets and per-partner data isolation before they're built, shipping security controls that are tricky for non-specialists to get right, while automating compliance, onboarding, and vendor work so the program mostly runs itself. Our models have moved beyond structure prediction into real therapeutic engineering, and the partnerships that come with that raise the bar every quarter. About you We index on judgment, breadth, and the instinct to build security in rather than bolt it on. The archetype is an engineer who specialized into security, thinks about the business as much as the threat model, and would rather partner with engineers than audit them. We look for: - 5+ years in security engineering, having built or meaningfully improved a security program at a high-growth company -- you have intuition for what a 30-person startup needs versus a 1,000-person one - ability to write targeted production code in python and typescript, not just scripts - startup or high-growth experience, working close to engineering rather than at arm's length - credibility and presence to represent Chai on calls with pharma CISOs - comfort owning detection, response, and incident management end to end - familiarity with SOC 2 and ISO 27001 as programs to run well, not boxes to check Life sciences or other regulated-industry experience is a bonus. A background in biology is not required. What makes the difference is technical excellence, business sense, and grit. WE OFFER The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

Listed by Chai Discovery for a position based in the United States. Employers on this board attest they are hiring domestically.

Biotech/Pharma

73 days ago

Research Associate or Associate Scientist, Genome Engineer

Conception · Berkeley, California, USA

Pay

Not listed

Setting

On-site

Apply Sign in to favorite Permalink

Experience level: Masters, PhD or equivalent experience. About Conception Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells. Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, and synthetic biology to make this vision a reality. The position - We are seeking a highly organized, rigorous, and hands-on Research Associate or Associate Scientist with strong experience in genome and cell engineering to help build tools that enhance Conception’s differentiation platform. In this role, you will generate engineered cell lines, including reporter lines, knock-out and knock-in lines, and overexpression lines to enable better tracking, control, and optimization of differentiation systems. - This position sits at the intersection of genome engineering, stem cell biology, assay development, and differentiation platform development. You will be responsible for designing, building and validating robust engineered cell systems using CRISPR-based approaches, DNA-integrating expression systems, and constitutive or inducible transgene expression platforms. The ideal candidate has strong hands-on experience with mammalian cell engineering, tissue culture, careful clonal line generation, molecular validation, and expression tracking, and is excited to apply these tools to complex differentiation systems. What you’ll do - Build engineered cell lines to support Conception’s differentiation platform, including reporter lines, knock-out lines, knock-in lines, and overexpression lines. - Use CRISPR-based genome engineering approaches to design, generate, screen, and validate edited cell lines. - Develop DNA-integrating expression systems for constitutive and inducible transgene expression during differentiation. - Optimize workflows for transfection, transduction, selection, clonal isolation, expansion, genotyping, and expression validation. Build assays to track reporter activity, transgene expression, silencing, differentiation state, and biological outcomes. - Support differentiation experiments using engineered lines to monitor and improve cell fate transitions. Collaborate across differentiation, organoid, cell engineering, and computational teams. What we’re looking for REQUIRED - Bachelor’s or Master’s degree in Cell Biology, Molecular Biology, Stem Cell Biology, Bioengineering, Genetics, Synthetic Biology, Developmental Biology, or a related field, or equivalent experience. - Hands-on experience with mammalian cell culture and cell engineering workflows. - Experience with CRISPR genome engineering, including knock-out, knock-in, or reporter line generation. Experience designing, generating, screening, and validating engineered cell lines using molecular and functional assays. - Experience with DNA delivery or integrating expression systems such as plasmid transfection, viral transduction, PiggyBac, Sleeping Beauty, lentiviral systems, or related approaches. - Experience with standard validation and readout assays such as PCR, genotyping, sequencing, flow cytometry, imaging, qPCR, reporter assays, or immunostaining. - Strong experimental execution, troubleshooting, documentation, organization, and data interpretation skills. PREFERRED - Experience with iPSCs, ESCs, primary cells, differentiating cells. - Experience building reporter lines to track gene expression, cell state, or differentiation. - Experience with inducible expression systems, constitutive expression systems, promoter testing, or transgene expression optimization. - Experience assessing or troubleshooting transgene silencing during extended culture or differentiation. - Experience with CRISPRa, CRISPRi, dCas9-based systems, or other gene modulation approaches. - Familiarity with stem cell differentiation, developmental biology, reproductive biology, germ cell development, ovarian biology, or organoid systems. Come and work with us We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions. ‍ To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104

Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.

Biotech/Pharma

75 days ago

Director, Clinical Science

Olema Oncology · Boston, Massachusetts

Pay

$220k–245k

Setting

On-site

Apply Sign in to favorite Permalink

Director, Clinical Science Boston, Massachusetts Apply Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon. Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC. Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day. If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond. About the Role >>> Director, Clinical Science As the Director, Clinical Science reporting to the Vice President, Clinical Science, you will play a key role in one of our ongoing clinical studies. You will work collaboratively in a multi-disciplinary team setting including Clinical Operations, Medical Monitors, Data Management, Biostatistics, Clinical Pharmacology, Regulatory and Program Management, in the planning, conduct and analysis of clinical trials. Your job contributes to and supports Olema’s mission of developing therapies that offer the potential to improve outcomes for women living with cancer. This role is based out of our San Francisco, CA or Cambridge, MA office and will require up to 20% travel. Your work will primarily encompass: Writing of technical and clinical documents including protocols, amendments, investigator’s brochures, and the clinical sections of regulatory documents Working with the study team to identify and track any potential safety events within a given trial Interacting with investigators and thought leaders in oncology to facilitate the design of clinical synopses and protocols Evaluate the safety, pharmacology, and efficacy of ongoing studies in close collaboration with the medical monitor and the safety, pharmacology and clinical operations teams Organizing and performing the study level and individual subject level analysis of the clinical trial data to gain insights and develop strategies for the clinical study report (CSR) writing Contributing to the writing and/or review product specific abstracts, publications and supporting the development of presentations for scientific meetings Maintaining clinical and technical expertise in the therapeutic area of oncology Attending scientific meetings pertinent to clinical science activities And will also include: Collaborating with the Medical Monitor on review of enrollment packets, clinical development plans and scientific presentations Collaborating with Clinical Operations and other internal study teams to develop Informed Consent Forms, Case Report Forms and CRF instructions Participating in ongoing clinical data review in collaboration with a cross functional team Collaborating with Clinical Operations and other team members in the development of agendas, training materials and presentation for site visits, investigator meetings and other study related activities Ensuring adherence to Olema’s Standard Operation Procedures and values, and maintaining the highest level of ethical behavior by leading by example Ideal Candidate Profile >>> A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. Knowledge: Advanced degree such as a PhD or PharmD is strongly preferred Experience in oncology clinical development is required Comprehensive knowledge of oncology clinical trial implementation and drug development process Demonstrated understanding of the clinical drug development process to execute drug development strategic plans and meet milestones Experience: A minimum of 8 years’ experience in biotech/pharmaceutical industry is required Strong knowledge of Good Clinical Practices (GCP), FDA, and EMEA/CHMP regulations and guidelines; familiarity with other international regulatory requirements is a plus Proactively identifying challenges/problems and proposing solutions with a strong sense of urgency Demonstrated success motivating both internal and external team members and collaborators, fostering and nurturing teamwork Attributes: Strong attention to detail Ability to interact effectively within a cross functional team Excellent written and oral communication skills Ability to work in a diverse and dynamic cross-functional team Passionate about the drug-development process Self-starter who thrives in a fast-paced environment The base pay range for this position is expected to be $220,000 - $250,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. Important Information >>> We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you. Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview. Apply for this job * indicates a required field First Name* Last Name* Preferred First Name Email* Phone Country* Phone* Location (City)* Locate me Resume/CV Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Home Address* City* State* Zip Code* LinkedIn Profile* Website Are you legally authorized to work in the United States?* Select... Do you now or will you in the future require employer sponsorship?* Select... Submit application Powered by

Listed by Olema Oncology for a position based in the United States. Employers on this board attest they are hiring domestically.

Biotech/Pharma

75 days ago

Director, Clinical Science

Olema Oncology · San Francisco, California

Pay

$220k–245k

Setting

On-site

Apply Sign in to favorite Permalink

Director, Clinical Science San Francisco, California Apply Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon. Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC. Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day. If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond. About the Role >>> Director, Clinical Science As the Director, Clinical Science reporting to the Vice President, Clinical Science, you will play a key role in one of our ongoing clinical studies. You will work collaboratively in a multi-disciplinary team setting including Clinical Operations, Medical Monitors, Data Management, Biostatistics, Clinical Pharmacology, Regulatory and Program Management, in the planning, conduct and analysis of clinical trials. Your job contributes to and supports Olema’s mission of developing therapies that offer the potential to improve outcomes for women living with cancer. This role is based out of our San Francisco, CA or Cambridge, MA office and will require up to 20% travel. Your work will primarily encompass: Writing of technical and clinical documents including protocols, amendments, investigator’s brochures, and the clinical sections of regulatory documents Working with the study team to identify and track any potential safety events within a given trial Interacting with investigators and thought leaders in oncology to facilitate the design of clinical synopses and protocols Evaluate the safety, pharmacology, and efficacy of ongoing studies in close collaboration with the medical monitor and the safety, pharmacology and clinical operations teams Organizing and performing the study level and individual subject level analysis of the clinical trial data to gain insights and develop strategies for the clinical study report (CSR) writing Contributing to the writing and/or review product specific abstracts, publications and supporting the development of presentations for scientific meetings Maintaining clinical and technical expertise in the therapeutic area of oncology Attending scientific meetings pertinent to clinical science activities And will also include: Collaborating with the Medical Monitor on review of enrollment packets, clinical development plans and scientific presentations Collaborating with Clinical Operations and other internal study teams to develop Informed Consent Forms, Case Report Forms and CRF instructions Participating in ongoing clinical data review in collaboration with a cross functional team Collaborating with Clinical Operations and other team members in the development of agendas, training materials and presentation for site visits, investigator meetings and other study related activities Ensuring adherence to Olema’s Standard Operation Procedures and values, and maintaining the highest level of ethical behavior by leading by example Ideal Candidate Profile >>> A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. Knowledge: Advanced degree such as a PhD or PharmD is strongly preferred Experience in oncology clinical development is required Comprehensive knowledge of oncology clinical trial implementation and drug development process Demonstrated understanding of the clinical drug development process to execute drug development strategic plans and meet milestones Experience: A minimum of 8 years’ experience in biotech/pharmaceutical industry is required Strong knowledge of Good Clinical Practices (GCP), FDA, and EMEA/CHMP regulations and guidelines; familiarity with other international regulatory requirements is a plus Proactively identifying challenges/problems and proposing solutions with a strong sense of urgency Demonstrated success motivating both internal and external team members and collaborators, fostering and nurturing teamwork Attributes: Strong attention to detail Ability to interact effectively within a cross functional team Excellent written and oral communication skills Ability to work in a diverse and dynamic cross-functional team Passionate about the drug-development process Self-starter who thrives in a fast-paced environment The base pay range for this position is expected to be $220,000 - $250,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. Important Information >>> We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you. Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview. Apply for this job * indicates a required field First Name* Last Name* Preferred First Name Email* Phone Country* Phone* Location (City)* Locate me Resume/CV* Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Home Address* City* State* Zip Code* LinkedIn Profile* Website Are you legally authorized to work in the United States?* Select... Do you now or will you in the future require employer sponsorship?* Select... Submit application Powered by

Listed by Olema Oncology for a position based in the United States. Employers on this board attest they are hiring domestically.

Biotech/Pharma

77 days ago

Associate Director, Analytical Development (Biologics)

Xaira Therapeutics · South San Francisco, California, United States

Pay

$172k–215k

Setting

On-site

Apply Sign in to favorite Permalink

Back to jobs Associate Director, Analytical Development (Biologics) South San Francisco, California, United States Apply About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role The Associate Director, Analytical Development (Biologics) will lead analytical development activities supporting biologics programs from preclinical development through clinical execution. This role will oversee method development, validation, transfer, stability programs, and external laboratory activities, while ensuring analytical strategies are aligned with program needs, phase-appropriate CMC development, and regulatory expectations. Key Responsibilities Lead the development, qualification, validation, and transfer of analytical methods across the product lifecycle for biologics programs. Support the selection and oversight of contract development and manufacturing organizations, and contract laboratories. Provide technical oversight for analytical methods supporting reference standards, starting materials, intermediates, release testing, stability testing, drug substance, and drug product. Manage analytical activities performed by external contract laboratories, ensuring scientific rigor, technical alignment, and compliance with applicable quality standards. Develop and implement analytical strategies appropriate for each stage of CMC development and consistent with evolving regulatory expectations. Author and provide technical review of relevant CMC sections for regulatory submissions, including INDs, IMPDs, BLAs, MAAs, and related filings. Design and manage non-GMP and cGMP stability programs for drug substance and drug product batches, providing scientific guidance to support shelf-life and expiry dating recommendations. Partner cross-functionally with Process Development, Manufacturing, Quality Assurance, Regulatory Affairs, and external partners to ensure analytical plans are integrated with overall program objectives. Provide analytical expertise in support of out-of-specification results, deviations, non-conformance investigations, root cause analyses, and CAPA development. Serve as a key member of the CMC and Technical Operations team, contributing to cross-functional execution, continuous improvement, and a strong quality culture. Qualifications PhD in analytical chemistry or related discipline with more than 8 years of industry experience or BS/MS degree with more than 15 years industry experience Demonstrated experience in analytical development, method validation, method transfer, and molecular stability management within a regulated biopharmaceutical or pharmaceutical environment. Strong working knowledge of biologics CMC development, including complex modalities such as multi-specifics, as well as cGMP expectations, quality systems, and regulatory submission requirements. Experience managing external consultants, contract laboratories, CMOs, or CDMOs, with a proven ability to drive technical alignment across internal and external stakeholders. Experience supporting biologics, protein therapeutics, or other complex modalities from early development through clinical-stage execution. Track record of authoring or reviewing CMC content for IND, IMPD, BLA, MAA, or related regulatory submissions. Hands-on experience with HPLC, UHPLC, and LC-MS, including SEC, RP, and IEX chromatography. Experience with drug product assays, stability testing, formulation-related analytical methods, such as CE-SDS, icIEF, binding and potency assays, and impurity/residual testing, including HCP, DNA, and residual Protein A, is preferred. Success Profile The successful candidate will be a collaborative and scientifically rigorous leader who balances strategic thinking with hands-on technical problem solving. This individual will communicate effectively across functions, manage external partners with accountability, and help deliver high-quality CMC outcomes in a fast-paced development environment. Compensation We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $172,000 - $215,000 annually; however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience. Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end. TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes. Get new jobs like this in your inbox We'll email you when Xaira Therapeutics posts a job like this one. Create alert Apply for this job * indicates a required field Autofill my application First Name* Last Name* Preferred First Name Email* Phone Country* Phone* Location (City)* Locate me Resume/CV* Attach Attach Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Attach Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Education School Select... Degree* Select... Discipline* Select... Add another Website LinkedIn Profile* Are you legally authorized to work in the country for this position without requiring employer-sponsored work authorization?* If you answered 'No' to the previous question, will you require sponsorship for a work visa or other work authorization?* This role is based in our South San Francisco office and requires five days per week in-office. How does this align with your preferences?* Describe your experience selecting and managing CRO/CDMO partners for analytical studies:* Describe your experience supporting biologics (protein/antibody therapeutics) from early discovery through clinical development* What excites you about the opportunity to work at Xaira?* Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Xaira Therapeutics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. Gender Select... Are you Hispanic/Latino? Select... Race & Ethnicity Definitions If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985. Veteran Status Select... Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 07/31/2029 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years. Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp. How do you know if you have a disability? A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to: Alcohol or other substance use disorder (not currently using drugs illegally) Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS Blind or low vision Cancer (past or present) Cardiovascular or heart disease Celiac disease Cerebral palsy Deaf or serious difficulty hearing Diabetes Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders Epilepsy or other seizure disorder Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome Intellectual or developmental disability Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD Missing limbs or partially missing limbs Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS) Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities Partial or complete paralysis (any cause) Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema Short stature (dwarfism) Traumatic brain injury Disability Status Select... PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete. Submit application Powered by

Listed by Xaira Therapeutics for a position based in the United States. Employers on this board attest they are hiring domestically.

Biotech/Pharma

86 days ago

Research Associate I, CFPS Production

BigHat Biosciences · San Mateo, CA, US

Pay

$75k–88k

Setting

On-site

Apply Sign in to favorite Permalink

Careers at Research Associate I, CFPS Production The role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate, CFPS Production role to manufacture, validate and execute experiments to develop cell-free protein synthesis (CFPS) reagents for BigHat’s high-throughput, automated platform for producing and characterizing antibodies. Key Responsibilities Manufacture and validate CFPS reagents used in BigHat’s high-throughput antibody screening platform including making buffers, media for biomass production and performing QC experiments on reagents. Maintain CFPS reagent manufacturing equipment including incubators, centrifuges, and homogenizers. Coordinate with lab ops team to request/order supplies for CFPS reagent manufacturing to ensure reliable stock for platform. Design and run experiments for development of next generation CFPS extract to optimize yield and purity of next generation antibodies on our platform. Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges. Present experimental plans and results during regular meetings with manager and science teams. Skills Knowledge and Expertise B.S. degree in Biochemistry, Molecular Biology, or related field with 1-2 years of industry experience. Experience working with recombinant protein expression from bacterial cultures. Experience with CFPS is highly desired but not required. Experience with molecular cloning techniques including primer design, PCR, mutagenesis, Golden Gate Assembly. Preferred: Experience and knowledge of protein purification methods including affinity chromatography and SEC. Excellent communication skills; organized and works well in small groups. Experience with quantitative and/or statistical analysis software is a plus (e.g. Excel, GraphPad Prism, Python, R, etc.) Experience with automation and high-throughput tools and robotic instrumentation is a plus. Total Rewards The salary estimated for this position is $75,000 - $88,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer. What BigHat Offers: Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived) Dental, and vision coverage through Guardian Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more 401(k) with company match DTO, two weeks of company-wide shutdown, and 12 company holidays Paid parental leave About BigHat Biosciences BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology. BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases. BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC. Apply Now Our Hiring Process Stage 7: Full Panel Interview Stage 8: Offer (Pending References) Stage 9: References Stage 10: Hired Stage 1: Applied Stage 2: Initial Recruiter Screen Stage 3: Initial Conversation | Head of Talent Stage 4: Initial Conversation | Hiring Manager Stage 5: 1st Technical Screen Stage 6: 2nd Technical Screen Stage 7: Full Panel Interview Stage 8: Offer (Pending References) Stage 9: References Stage 10: Hired Stage 1: Applied Stage 2: Initial Recruiter Screen Stage 3: Initial Conversation | Head of Talent Stage 4: Initial Conversation | Hiring Manager Stage 5: 1st Technical Screen Stage 6: 2nd Technical Screen Stage 7: Full Panel Interview Stage 8: Offer (Pending References) Stage 9: References Stage 10: Hired 1 2 3 Not quite right? Register your interest to be notified of any roles that come along that meet your criteria. Register Your Interest Apply Now Department Lab Science Employment Type Full Time Location San Mateo, CA Workplace type Onsite This role's hiring manager: Adam Carr View Adam's Profile View all opportunities at BigHat Biosciences BIGHAT BIOSCIENCES PRIVACY POLICY COOKIES POWERED BY Cookies We use cookies to ensure you get the best experience on our website. Accept all Reject all Settings

Listed by BigHat Biosciences for a position based in the United States. Employers on this board attest they are hiring domestically.

Select a role

The full posting opens here — pay, setting and the full description, without leaving the list.