Millwright Augusta, Georgia, United States, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biomanufacturing today.

We are seeking a highly motivated Millwright to assist with capital projects, recommissioning, startup, and maintenance activities. The ideal candidate will have expertise in mechanical systems including: pumps, hydraulics, rotating equipment, laser alignment, and mechanical seals. Familiarity with electrical systems is a plus. This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative applied to the various duties and aspects of the position. This person will be expected to play an integral part of Manus’ team located in Augusta, GA.

Why work at Manus Bio:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:

• Analyzes mechanical and operational problems on equipment. Takes necessary corrective actions to maintain equipment within proper operating specifications.
• Examines, tests and measures equipment for normal operation using gauges, instruments and records data on appropriate forms.
• Make preventive maintenance checks and inspections of equipment, reports findings to supervisor/team. Completes appropriate documentation and develops a follow-up action plan if required.
• Participates in required training and helps train new employees and retrain current employees within the assigned work area.
• Inspect new and used parts to determine proper tolerance, wear patterns, etc., using rules, calipers, micrometers, and other measuring instruments.
• Makes repairs necessary to maintain equipment per manufacturer specifications using hand tools and power tools. Must be able to operate hand tools in a safe and efficient manner.
• Operates lathe, drill press, grinder and other metalworking tools as required to make or repair parts.
• Must have computer skills that would enable them to create work orders, word documents and order parts through SAP.
• Comply with all documentation requirements regarding processing GMPs, safety, housekeeping, environmental and sanitation. All work must be done in compliance with company guidelines for safety and environment responsibility.
• Can operate within a team-based environment, willing to participate in team activities, serve in Leadership roles, and be receptive to receiving and giving constructive feedback to their team members and management.
• Must be able to follow detailed instructions as well as work in a safe and responsible manner.
• Must be able to function responsibly as part of a team.
• Must by physically able to handle equipment up to 50 kilograms using available equipment. Must be able to lift 40-pound containers repetitively. Must be able to wear required protective equipment, including respirators. Must be able to climb stairs and ladders repetitively when required.
• Work schedule will vary during shutdowns and other extraordinary conditions to include shift work.
• Must be able to follow minimal instructions and support safe work practices.

Required Qualifications:

• High School Diploma or GED.
• 5 years’ experience in the field of mechanical maintenance.
• Previous experience with hydraulics, rotating equipment, laser alignment, mechanical seals.
• Clear understanding and experience adhering to energy isolation/lockout tagout (LOTO) requirements.
• Possess strong communication (written & spoken) and interpersonal skills.
• Must be able to climb stairs and ladders when required.
• Execute the job function with minimal oversite.
• Must be able to wear required personal protective equipment (PPE).
• Experience with various computer applications in a Microsoft Windows environment.
• Work schedules may vary during outages, shutdowns, or other extraordinary conditions. This position must be able to provide support during these times.

Preferred Qualifications:

• Demonstrated ability to weld.
• Ability to troubleshoot using a model.
• Experience working in cGMP environments

Scientist II - High-Throughput Screening & Analytical Chemistry - Waltham, MA, Full-time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biotechnology today.

We are seeking a Scientist in Screening & Analytical Chemistry to lead development of high-throughput analytical workflows. This role focuses on method development for rapid, targeted metabolite quantification and integration with screening pipelines.

This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus’s research and development team located in Waltham, MA.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.

• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.

• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities

• Develop and optimize analytical methods for targeted metabolite quantification
• Lead method development on GC/MS, GC-FID, and LC-QQQ-MS platforms
• Design high-throughput analytical workflows with fast cycle times
• Develop sample preparation and derivatization strategies
• Work with automation and screening teams to support microtiter plate-based fermentations
• Analyze and interpret large datasets
• Mentor junior staff
• Interface with instrument vendors to maintain uptime and optimal performance
• Author SOPs and technical reports

Basic Qualifications

• PhD in Analytical Chemistry, Chemistry, or related field OR
• MS with 8+ years or BS with 13+ years relevant experience
• Strong experience in analytical method development

Required Technical Expertise

• GC-FID and GC/MS assay development for targeted quantitation and metabolite profiling
• LC/QQQ-MS assay develop for targeted quantitation
• Assay optimization for speed, sensitivity, and throughput

Preferred Experience

• Experience with high-throughput screening environments
• Integration of analytical workflows with automation
• Familiarity with liquid handling platforms
• Experience with LIMS (e.g. Benching) and large datasets
• Industrial biotech or applied R&D experience
• Experience with the following types of analytical instrumentation
  • UHPLC
  • GC-FID
  • GC/MS
  • LC/QQQ-MS
• Experience with a variety of sample extraction and preparation techniques, applying automated solutions when appropriate, from complex matrices
  • Microbial fermentation broth
  • Microbial biomass
  • Purified extracts

Maintenance Planning Engineer
Augusta, Georgia, United States, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self-motivated and highly organized individual for a position that will specialize in and lead all laboratory operations at our Boston BioFacility.

Why work at Manus Bio:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenges and hard work that comes with working on the cutting edge.

Responsibilities:

• Ensuring safety is the first goal of getting any task completed.
• Encouraging the execution of permits and use of all required PPE.
• Participating in PSSRs, risk assessments, and RCAs as needed.
• Maintain accurate SDS documentation for all lubricants and chemicals stored in maintenance.

• Plan maintenance activities across all Manus Bio facilities in Augusta, including but not limited to Sand 81, Fermentation, Utilities, and Waste Treatment.
• Develop preventative maintenance schedules according to specific machinery/unit operations. Create additional PMs for equipment that is not currently included. Set PM frequency per manufacturer requirements.
• Ensure that repairs and projects are done in a timely manner and meet the company’s expectations.
• Utilize MaintainX to coordinate planning, and interface with other stakeholders to implement features that will optimize workflow.
• Obtain and report weekly maintenance KPIs to management and adjust as needed.
• Schedule weekly planning meetings with the appropriate maintenance, utilities, and production personnel to finalize maintenance plans for the following week.
• Continued development of equipment BOM structure within MaintainX for all assets currently in use.
• When necessary or useful, propose and implement schemes or additional software to make planning more efficient.
• Demonstrate flexibility and creativity to shift activity and schedules with company demand.
• Expedite work orders and plan projects quickly with changing activity.

• Develop, plan and execute the annual Site Shutdown. Supervise maintenance activities according to the shutdown schedule and work closely with production on equipment downtime availability. This includes all necessary equipment inspections, including the following:
  • PRV and pressure vessels, back-flow preventors, and boilers/DAs.
• Organize internal maintenance projects and ensure work orders reflect the work being performed. Review all critical information with the appropriate personnel prior to performing the work.
• Develop strong working relationships with vendors/contractors and ensure that all contractor information is accurate in the contractor management system. This includes safety training, COI, and safety records.
• Maintain maintenance plans and review with designated crews for seamless execution.

• Ensure that all contracts on service agreements and inspections are updated accordingly. This includes services for the following equipment:
  • Air compressors, cranes and hoists, process dryers (suppression systems), site elevators, lift truck fleet, HVAC and chillers.
• Acquire any rental equipment necessary to support the production and maintenance departments. This includes but is not limited to the following:
  • HVAC, Dehumidifiers, scaffolding, lift trucks, cranes, compressors, and chillers.
• Perform all facility repairs as needed with the assistance of outside resources. This includes but is not limited to the following:
  • Underground repairs, clearing of drainage, roofing repairs, sheet metal, and demolition work.

• Obtain all POs prior to performing services or receiving materials/goods.
• Maintain a running list of all purchases made, and associated details.
• Receive all invoices in SAP to meet month-end deadlines.

• Maintain accurate documentation records per existing file structure. Some documents can also be saved on the associated work order in MaintainX for future reference. This includes but is not limited to the following:
  • Equipment, Instrumentation, service agreements, accounting (quotes, purchase orders, invoices), projects, safety (PSSRs, risk assessments, RCAs), and facility repairs.

Work Environment:

• Work is performed in an office and uncontrolled atmospheres. Exposure to harsh conditions—such as: dust, fumes, chemicals, hazardous materials, noise, and varying weather and temperatures—for short periods of time is possible. All employees are required to follow safety standards and wear all personal protective equipment in designated areas.
• While performing the duties of this position, the employee is regularly required to walk, stand, use hands and fingers, grip, handle or feel, reach with hands and arms, climb or balance, stoop, kneel, crouch or crawl, and talk and hear. The ability to lift and carry 10 pounds on a regular basis is required.

Required Qualifications:

• 0-5 years' experience in maintenance planning
• Excellent communication skills; both oral and written are required.
• Strong analytical and problem-solving skills are required.
• Computer skills and an in-depth knowledge of Microsoft Windows based programs are required.
• Ability to work flexible hours.
• Requires effective time management skills, personal conduct, and change management abilities.
• Ability to effectively interact with co-workers, vendors, contractors and other business contacts.
• Must comply with Manus Bio’s core values for the safe and efficient operation of the business and maintaining sound relationships among and with employees.

Preferred Qualifications:

• Experience working in cGMP environments.
• Experience working with CMMS systems (SAP, FIIX, etc.)
• Proficiency in utilizing Microsoft applications (word, excel, power point, etc.)
• Experience in biochemical, petrochemical, pharmaceutical, energy, oil and gas industries are preferred.

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

The Chemical/Fermentation Plant Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance, equipment reliability, and operations. Creativity and decision-making skills are required. Must be able to maintain a good working relationship with all personnel. Work as a member of the fermentation plant team which includes assisting in the Pilot Plant. Controls, monitors, and measures fermentation processes as instructed. Abides by all safely, environmental, and quality requirements. Perform minor maintenance and duties related to product testing, including sampling.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities:

Interface with production to provide resources to solve fermentation and product isolation problems. Execute and help evaluate fermentation experiments. This activity includes:

• Prepare fermentation and downstream equipment in accordance to SOPs, this include equipment setup, media make up, equipment disassembly, cleaning, etc.
• Collect samples during manufacturing process for analytical analysis.
• Prepare all required batch records, reflect constantly changing experimental designs and ensure clear communication to the process development subject matter expert of the targeted design parameters.
• Collect and review all batch records. Data reduction includes electronic data conversion into and formatting in Excel for purposes of trending key operational parameters. Data is reviewed and checked. Off-line analytical data is reviewed for accuracy, retesting if necessary. Final results are organized and distributed to the process development subject matter expert.
• Coordinate day-to-day Fermentation Plant activities, including manufacturing scheduling conflicts, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
• Prepare SOP for new process or operations as needed.
• Assist and provide hands-on support of Fermentation Plant maintenance activities, including rebuilding of probes and housings, changing out gear boxes on vessels, rebuilding valves, piping modifications, and modifying/fabricating new and existing equipment.
• Maintain the upkeep of the Fermentation Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; Use your own tools to correct minor maintenance issues is encouraged.
• Adhere to company EH&S policies and procedure. Ensure fermentation plant compliance with safety and environmental regulations.
• Physical demand requirements are in excess of sedentary work due to inspection of equipment. Must be able to climb stairs and ladders.
• Must be able to wear required protective equipment including respirators (if needed).
• Work schedule is considered day shift but will vary depending on manufacturing plan and other extraordinary conditions.
• Ensure Fermentation plant compliance with safety and environmental regulations.

Required Qualifications:

• High school diploma or GED equivalent.
• Minimum of 3 years fermentation or related plant operator experience.
• Must be able to follow minimal instructions and support safe work practices.

• Must be an excellent team member with strong communication skills and a desire to work collaboratively.
• Must be flexible with day-to-day duties and able to thrive in a start-up environment.
• Must hold themselves to the highest professional and ethical standards.
• Familiar with the production fermentation and downstream processes and equipment as well as microbiological and analytical laboratory procedures.
• Demonstrates flexibility in job rotations/various assignments.
• Basic PC skills which include Windows, Microsoft Office.

Preferred Qualification and Working Style:

• SAP skills
• Certified Train the Trainer skills
• Delta V controls experience

Job Type: Regular, Full-Time

Employee Status: Permanent

Industrial PainterAugusta, Georgia, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a skilled and detail-oriented Industrial Painter to join our team. The successful candidate will be responsible for preparing surfaces, applying paints and coatings, and ensuring high-quality finish on industrial equipment, structures, and surfaces. This role requires knowledge of various painting techniques, safety standards, and the ability to work in diverse environments.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenges and hard work that comes with working on the cutting edge.

Responsibilities:

• Prepare surfaces for painting by cleaning, sanding, and applying primers or sealants.
• Mix and apply paints, coatings, and finishes using brushes, rollers, or spray equipment.
• Interpret blueprints, drawings, and specifications to determine painting requirements.
• Operate and maintain painting tools and equipment, including spray guns, compressors, and scaffolding.
• Ensure proper ventilation and safety measures are in place during painting operations.
• Inspect finished surfaces for quality and touch up as needed.
• Maintain a clean and organized work area.
• Follow all safety protocols and environmental regulations.

Qualifications:

• High school diploma or equivalent; vocational training in painting or a related field is a plus.
• Proven experience as an industrial painter or similar role.
• Familiarity with painting techniques, surface preparation, and coating types.
• Ability to work at heights and in confined spaces.
• Strong attention to detail and commitment to quality.
• Physical stamina and manual dexterity.
• Knowledge of safety procedures and hazardous materials handling.

Preferred Skills:

• Certification in industrial painting or coating application (e.g., NACE, SSPC).
• Experience with abrasive blasting or powder coating.
• Forklift or aerial lift certification.

Working Conditions:

• Exposure to fumes, chemicals, and varying temperatures.
• Use of personal protective equipment (PPE) is required.
• May involve working in noisy, dusty, or outdoor environments.

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a Process Control Engineer – I to assist engineers on project work, including design, configuration and commissioning. This person will also support production areas to reduce downtime and improve processes and will be expected to play an integral part within the company.

Why work for the Company:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:

• Interface with Production staff to develop new or improved process designs as it pertains to control software and hardware. This would include increased efficiency, higher levels of automation, improved methods of control, and improved information gathering and reporting. Work with engineering group to implement these designs.
• Provide technical support to Production in the area of control system configuration and process control parameter changes, as well as process troubleshooting.
• Work within a team to introduce and recommend changes in control schemes that will improve the plant operation.
• Develop, maintain, and proctor training procedures for console operators to assure development of good operating practices on automated systems. This includes the development of training materials and process simulation.
• Maintain good documentation practices in accordance to the plant site GMP guidelines.
• Develop a working knowledge of multiple control systems on site (PLC and DCS.) Provide backup support to other process control personnel.
• Supports area capital projects, including scope development, cost justification, control logic, and commissioning.
• Supports site safety and quality initiatives through participation & leadership in teams, incident/CAR analysis, and follow-up.

Working Style:

• Proven reliability and work ethic
• Excellent verbal and written communication skills
• Strong analytical and problem-solving skills
• Understanding of safety, health, environmental, quality systems, and regulatory compliance guidelines.

Required Qualifications:

• B.S Degree in Engineering
• Knowledge of automation control platforms such as PLC/HMI or DCS
• Must be able to follow minimal instructions and support safe work practices
• Must be able to function responsibly as part of a team.
• Demonstrated ability to interact with facility employees, contract personnel, and with outside vendors and customers.
• Must be able to follow detailed instructions as well as work in a safe and responsible manner.
• Physical demand requirements are in excess of sedentary work due to equipment inspection and troubleshooting.
• Must be able to climb stairs and ladders.
• Must be able to wear required protective equipment.
• Work schedule will vary during shutdowns and other extraordinary conditions.
• Displayed ability to learn quickly and driven to broaden knowledge base
• Excellent computer skills

Preferred Qualifications:

• Familiarity of process instrumentation, controls engineering, and structured programming techniques.
• Basic level programming knowledge.

• Allen Bradley Platforms : HMI Factory Studio / RS Logix 5000.

• Communication protocols for communication with other PLC manufacturers

• Electrical and/or mechanical aptitude.