About Profound Research

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

Our Mission: Improving lives by providing advanced therapeutic options 

Our Vision: Creating the absolute best patient-physician experience in clinical research 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered 

• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues 

• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency 

• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards 

Why This Role Exists 

Patients are at the center of everything Profound does, and patient recruitment is one of the most direct ways we deliver on our mission of expanding access to advanced therapeutic options.  

 

As we continue to grow, we are looking for a senior leader to own and scale our patient engagement and recruitment function across our national site network. This leader will shape the strategy, team, processes, and operating model that help connect the right patients to the right trials faster while preserving the personal, trusted experience that defines Profound.  

 

Today, most of our patient recruiters are embedded within site teams, with a smaller centralized team providing additional support. This role will help evolve how those models work together as we scale, bringing clinical research experience, strong people leadership, and creative problem solving to how we recruit, engage, and support patients.  

 

This is a hands-on builder role for someone who is energized by growth, comfortable with ambiguity, and excited to create a patient recruitment function that is both highly effective and deeply patient-centered.  

  

What You’ll Own 

Patient Recruitment Strategy & Operating Model 

• Own Profound’s patient engagement and recruitment strategy across sites, studies, and therapeutic areas 

• Lead the continued evolution of Profound’s recruitment operating model, including embedded, centralized, and hybrid support, to improve enrollment performance and patient experience as we scale 

• Build scalable approaches to patient identification, outreach, engagement, pre-screening, scheduling, and retention in partnership with Clinical Operations 

• Establish clear priorities, goals, and accountability structures for the patient recruitment function 

• Translate organizational growth goals, study needs, and site realities into practical recruitment strategies 

• Partner with Clinical Operations, Commercial, Study Startup, Quality, Clinical Systems, Finance, and People to ensure recruitment strategies are aligned, compliant, and executable 

 

Enrollment Performance & Functional Execution 

• Own recruitment performance across the patient funnel, including lead quality, outreach effectiveness, pre-screening, scheduling, show rates, screening conversion, enrollment outcomes, and retention support 

• Establish the KPIs, dashboards, reporting rhythms, and forecasting needed to create visibility into recruitment performance 

• Use data to identify trends, risks, opportunities, and resourcing needs across the function 

• Lead study- and site-level recruitment planning for priority trials, ensuring the right strategies and resources are in place to support enrollment goals 

• Bring structure and urgency to recruitment execution while maintaining flexibility for the needs of different studies, sites, and patient populations 

 

Patient Engagement & Experience 

• Ensure Profound’s recruitment practices reflect a compassionate, service-oriented, and patient-centered experience 

• Strengthen the patient journey from initial engagement through screening and enrollment in partnership with Clinical Operations 

• Develop approaches that expand access to clinical research for diverse patient populations and support community-based recruitment 

• Identify opportunities to improve patient communication, follow-up, and retention without creating unnecessary complexity for sites or patients 

 

Team Leadership & Function Building 

• Lead and develop Profound’s patient recruitment team, including embedded and centralized team members 

• Build a high-performing culture rooted in accountability, urgency, collaboration, compassion, and continuous improvement 

• Clarify roles, responsibilities, performance expectations, and career pathways within the patient recruitment function 

• Build the team structure, leadership capabilities, staffing plans, and ways of working needed to support continued growth 

• Coach and develop leaders and team members to strengthen recruitment execution, patient communication, problem solving, and cross-functional partnership 

 

Process, Technology, & Continuous Improvement 

• Own the recruitment process and technology roadmap in partnership with Clinical Systems, IT, and operational leaders 

• Identify opportunities to improve consistency, visibility, efficiency, and scalability across recruitment workflows 

• Evaluate and implement tools, systems, vendor partnerships, and digital engagement strategies that improve recruitment performance and patient experience 

• Ensure recruitment processes remain compliant with clinical research, privacy, IRB, and patient communication requirements 

• Lead change management related to recruitment processes, technology, operating model, and performance expectations 

 

Requirements 

 

Essential Qualifications 

• Bachelor's degree in life sciences, healthcare administration, public health, business, or a related field; equivalent experience may also be considered 

• Meaningful experience in clinical research, patient recruitment, clinical operations, healthcare operations, or a closely related environment 

• Experience supporting or leading patient recruitment, enrollment, patient engagement, pre-screening, or site-level clinical research operations 

• Practical understanding of how patients move through the clinical trial recruitment process, including outreach, pre-screening, scheduling, screening, enrollment, and retention 

• Experience leading teams, projects, or cross-functional initiatives in a growing, multi-site, remote, or geographically dispersed environment 

• Strong people leadership skills, including the ability to coach, develop, motivate, and hold teams accountable 

• Ability to use data, site feedback, and operational insights to identify opportunities and improve performance 

• Strong cross-functional partnership skills, with the ability to build trust across clinical, operational, commercial, technology, finance, and people teams 

• Working knowledge of clinical research compliance considerations, including patient privacy, IRB-approved recruitment materials, GCP principles, and ethical patient engagement 

• Strong communication skills, sound judgment, initiative, and comfort working in a fast-paced, evolving environment 

 

Preferred Qualifications 

• Experience in a clinical research site network, SMO, CRO, sponsor, healthcare services organization, or community-based research environment 

• Experience with embedded, centralized, or hybrid patient recruitment models 

• Prior experience working directly with patients or in a patient-facing clinical research, healthcare, or recruitment capacity 

• Experience leading patient recruiters, patient engagement specialists, call center teams, clinical research staff, or other patient-facing operational teams 

• Experience with recruitment technology, CRM platforms, contact center tools, scheduling systems, patient engagement platforms, or clinical trial recruitment vendors 

• Experience developing or using KPIs, dashboards, productivity expectations, or capacity planning tools 

• Knowledge of digital recruitment, community outreach, physician referral workflows, patient databases, or other patient acquisition strategies 

• Experience supporting growth, change, or function-building in a startup or high-growth environment 

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Physical Requirements & Work Environment

• This role is primarily performed in a remote/office environment and requires prolonged periods of sitting or standing at a desk, working on a computer, and participating in virtual meetings 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials 
• Minimal travel to company sites, meetings, or partner locations may be required, including the ability to navigate office/clinical environments and transport typical work materials 
• Must be able to maintain a productive and professional remote work setup with reliable internet connectivity
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role 

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Broad Organizational Exposure: Gain visibility across the full lifecycle of clinical research – from study startup through closeout – working cross-functionally with clinical, finance, and operations teams
• Flexible Work Environment: This role offers the autonomy of a remote or hybrid work setting while keeping you connected to a team that’s deeply collaborative and mission-driven

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Why This Role Exists 

If you’re ready to bring your clinical research experience into a fast-paced, high-volume environment, this role offers an opportunity to make an immediate impact.  

 

As a Clinical Research Coordinator I at Profound Research, you’ll support the execution of high-volume vaccine clinical trials at one of our sites. You’ll help manage study activities, lead participant visits, complete protocol-required procedures and documentation, and work closely with investigators, sponsors, CROs, and internal teams. This is not an entry-level support role – you’ll be expected to operate with ownership, sound judgment, and a strong understanding of clinical research standards.   

 

This is a 1099 contract opportunity designed to support near-term vaccine study needs, with the potential to convert to a full-time position based on business needs, performance, and role availability. If you’re looking to build on your clinical research experience with a growing organization that values accountability, quality, and patient-centered execution, we’d like to hear from you.  

 

What You’ll Do 

 

• Serve as a coordinator for assigned vaccine clinical trials, supporting study activities from start-up through closeout as needed 

• Execute participant visit flow independently, including visit preparation, patient interaction, protocol-related procedures, data collection, and documentation 

• Support high-volume clinic days by helping maintain efficient visit flow, clear communication, and accurate completion of study-required tasks 

• Lead patient interactions with clarity and compassion, ensuring participants feel informed and supported throughout their study experience 

• Perform clinical procedures as required by protocol, which may include vital signs, EKGs, phlebotomy, specimen collection, specimen processing, and other study-specific assessments 

• Maintain accurate, timely, audit-ready documentation across source documents, CRFs, EDC systems, CTMS platforms, and other study tools 

• Track, document, and escalate adverse events, deviations, safety findings, and protocol-related issues in accordance with study and regulatory requirements   

• Communicate directly and professionally with investigators, sponsors, CROs, monitors, vendors, and internal team members 

• Support site readiness for monitoring visits, sponsor communications, internal quality review, and audits 

• Follow study protocols, SOPs, Good Clinical Practice, Good Documentation Practices, and infection control expectations to support compliant, high-quality trial execution 

• Help maintain organized study materials, lab workflows, visit supplies, and documentation needed for efficient site operations 

• Contribute to a fast-paced, team-based environment where quality, urgency, patient experience, and data integrity all matter 

 

What We’re Looking For 

You have clinical research experience and are ready to operate with more ownership. You’re organized, detail-oriented, comfortable managing competing priorities, and able to follow through without heavy oversight.  

 

Essential Qualifications 

• Bachelor’s degree with 1+ year of relevant experience, OR Associate’s degree with 3+ years of relevant experience, OR High school diploma with 4+ years of relevant experience and at least 1 year of CRC experience 

• Prior experience in clinical research, including exposure to clinical trial coordination, study visits, source documentation, and protocol-driven workflows 

• Experience performing or supporting clinical procedures, which may include vital signs, EKGs, phlebotomy, specimen collection, specimen processing, or lab-related workflows 

• Comfortable working independently in a fast-paced, site-based clinical research environment  

• Ability to support high-volume patient visits while maintaining accuracy, professionalism, and a patient-centered approach 

• Strong documentation skills and understanding of audit-ready clinical research standards 

• Familiarity with EDC platforms, clinical trial management systems, eSource tools, EMRs, lab portals, or other clinical documentation systems 

• Working knowledge of Good Clinical Practice, Good Documentation Practices, protocol adherence, and regulatory expectations 

• Strong communication skills with the ability to interact professionally with patients, caregivers, investigators, site staff, sponsors, CROs, monitors, and internal teams 

• Ability to maintain professionalism, confidentiality, and care when working with patients and sensitive information 

 

Preferred Qualifications 

• Experience supporting vaccine studies, infectious disease studies, immunization clinics, urgent care, primary care, or other high-volume patient-facing clinical environments 

• Prior experience serving as a primary or lead coordinator for assigned studies 

• Experience with adverse event documentation, protocol deviations, query resolution, monitoring visits, and sponsor/CRO communication 

• Active or prior ICH-GCP, IATA, phlebotomy, or related clinical research certifications 

• Experience supporting start-up, closeout, or audit/monitoring readiness activities 

• Comfort adapting quickly to study-specific workflows, systems, and enrollment timelines 

 

Engagement Details 

This is a 1099 independent contractor opportunity designed to support current high-volume vaccine study needs while giving the right person a chance to learn, contribute quickly, demonstrate ownership, and be considered for future opportunities. For contractors who perform well and align with business needs, there may be an opportunity to be considered for full-time employment over time. 

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Why This Role Exists 

If you’re curious about how new treatments and vaccines reach patients, detail-oriented by nature, and energized by work that genuinely matters, this is an opportunity to gain hands-on experience in clinical research. 

 

As an Assistant Clinical Research Coordinator at Profound Research, you’ll work alongside experienced clinical research staff at one of our sites, supporting the day-to-day execution of high-volume vaccine clinical trials. You’ll learn by doing – gaining hands-on experience in study coordination, patient interaction, data collection, and clinical procedures in a fast-paced, site-based research environment. 

 

This is a 1099 contract opportunity to designed to support near-term vaccine study needs, with the potential to convert to a full-time position based on business needs, performance, and role availability. Whether you’re looking to build on prior clinical or research experience or take the next step into the field, this is an opportunity to contribute to meaningful work with a growing organization that values ownership, attention to detail, and patient-centered service. 

 

What You’ll Do 

 

• Support the coordination of high-volume vaccine clinical trials, including patient visits, scheduling, and study-related procedures 

• Assist with data collection and documentation while learning to apply the rigorous standards that clinical research requires 

• Perform and develop competency in clinical procedures including vital signs, EKGs, phlebotomy, and specimen processing 

• Help prepare for and support efficient participant visits, including rooming patients, organizing supplies, preparing visit materials, and keeping the site team aligned during busy clinic days 

• Interact directly with study participants by greeting them, explaining visit steps, answering process-related questions within scope, and ensuring they feel supported throughout the visit 

• Work closely with Clinical Research Coordinators and site leadership, asking questions, seeking feedback, and building your clinical research knowledge 

• Follow study protocols, SOPs, Good Clinical Practice, Good Documentation Practices, and infection control expectations to support compliant, audit-ready trial execution 

• Help maintain organized study materials, supplies, documentation, and lab-related workflows needed for patient visits and site operations 

• Communicate clearly with site team members regarding patient needs, visit flow, documentation status, specimen handling, and study-related tasks 

• Contribute to a fast-paced, team-based site environment where quality, urgency, and patient experience all matter 

 

What We’re Looking For 

You don’t need to have done this exact job before. You need to be the kind of person who takes ownership of their work, communicates clearly, pays close attention to detail, and genuinely cares about the patient experience. The rest we’ll help you build.  

 

Essential Qualifications

High school diploma or technical degree with 3+ years of relevant experience in life sciences, OR Associate’s degree with 1+ year of relevant experience, OR Bachelor’s degree with relevant coursework or experience in a clinical or life sciences setting 

• Comfortable working in a fast-paced, team-based environment 

• Strong attention to detail and ability to follow structured processes accurately 

• Clear, professional communication with patients, caregivers, clinical staff, and internal team members 

• Proficient with standard computer tools; able to learn new systems quickly 

• Familiarity with medical terminology and basic clinical procedures 

• Ability to maintain professionalism, confidentiality, and care when working with patients and sensitive information 

 

Preferred Qualifications 

• Prior clinical research experience, especially in a clinical research coordinator, assistance clinical research coordinator, research assistant, or patient-facing site support role 

• Experience supporting vaccine studies, infectious disease studies, immunization clinics, urgent care, primary care, or other high-volume patient-facing clinical environments 

• Experience with phlebotomy, specimen collection, specimen processing, vital signs, EKGs, or other clinical procedures 

• Prior exposure to Good Clinical Practice, source documentation, regulated healthcare environments, or audit-ready documentation standards 

• Experience using electronic medical records, CTMS platforms, eSource systems, lab portals, or other clinical documentation systems 

 

Engagement Details 

This is a 1099 independent contractor opportunity designed to support current high-volume vaccine study needs while giving the right person a chance to learn, contribute, and demonstrate readiness for future opportunities. For contractors who perform well and align with business needs, there may be an opportunity to be considered for full-time employment over time.  

 

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Why This Role Exists 

If you’re curious about how new treatments and vaccines reach patients, detail-oriented by nature, and energized by work that genuinely matters, this is an opportunity to gain hands-on experience in clinical research. 

 

As an Assistant Clinical Research Coordinator at Profound Research, you’ll work alongside experienced clinical research staff at one of our sites, supporting the day-to-day execution of high-volume vaccine clinical trials. You’ll learn by doing – gaining hands-on experience in study coordination, patient interaction, data collection, and clinical procedures in a fast-paced, site-based research environment. 

 

This is a 1099 contract opportunity to designed to support near-term vaccine study needs, with the potential to convert to a full-time position based on business needs, performance, and role availability. Whether you’re looking to build on prior clinical or research experience or take the next step into the field, this is an opportunity to contribute to meaningful work with a growing organization that values ownership, attention to detail, and patient-centered service. 

 

What You’ll Do 

 

• Support the coordination of high-volume vaccine clinical trials, including patient visits, scheduling, and study-related procedures 

• Assist with data collection and documentation while learning to apply the rigorous standards that clinical research requires 

• Perform and develop competency in clinical procedures including vital signs, EKGs, phlebotomy, and specimen processing 

• Help prepare for and support efficient participant visits, including rooming patients, organizing supplies, preparing visit materials, and keeping the site team aligned during busy clinic days 

• Interact directly with study participants by greeting them, explaining visit steps, answering process-related questions within scope, and ensuring they feel supported throughout the visit 

• Work closely with Clinical Research Coordinators and site leadership, asking questions, seeking feedback, and building your clinical research knowledge 

• Follow study protocols, SOPs, Good Clinical Practice, Good Documentation Practices, and infection control expectations to support compliant, audit-ready trial execution 

• Help maintain organized study materials, supplies, documentation, and lab-related workflows needed for patient visits and site operations 

• Communicate clearly with site team members regarding patient needs, visit flow, documentation status, specimen handling, and study-related tasks 

• Contribute to a fast-paced, team-based site environment where quality, urgency, and patient experience all matter 

 

What We’re Looking For 

You don’t need to have done this exact job before. You need to be the kind of person who takes ownership of their work, communicates clearly, pays close attention to detail, and genuinely cares about the patient experience. The rest we’ll help you build.  

 

Essential Qualifications

High school diploma or technical degree with 3+ years of relevant experience in life sciences, OR Associate’s degree with 1+ year of relevant experience, OR Bachelor’s degree with relevant coursework or experience in a clinical or life sciences setting 

• Comfortable working in a fast-paced, team-based environment 

• Strong attention to detail and ability to follow structured processes accurately 

• Clear, professional communication with patients, caregivers, clinical staff, and internal team members 

• Proficient with standard computer tools; able to learn new systems quickly 

• Familiarity with medical terminology and basic clinical procedures 

• Ability to maintain professionalism, confidentiality, and care when working with patients and sensitive information 

 

Preferred Qualifications 

• Prior clinical research experience, especially in a clinical research coordinator, assistance clinical research coordinator, research assistant, or patient-facing site support role 

• Experience supporting vaccine studies, infectious disease studies, immunization clinics, urgent care, primary care, or other high-volume patient-facing clinical environments 

• Experience with phlebotomy, specimen collection, specimen processing, vital signs, EKGs, or other clinical procedures 

• Prior exposure to Good Clinical Practice, source documentation, regulated healthcare environments, or audit-ready documentation standards 

• Experience using electronic medical records, CTMS platforms, eSource systems, lab portals, or other clinical documentation systems 

 

Engagement Details 

This is a 1099 independent contractor opportunity designed to support current high-volume vaccine study needs while giving the right person a chance to learn, contribute, and demonstrate readiness for future opportunities. For contractors who perform well and align with business needs, there may be an opportunity to be considered for full-time employment over time.  

 

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Why This Role Exists

 

At Profound Research, the Principal Investigator is the clinical cornerstone of everything we do at the site level. In this role, you’ll provide the medical expertise and oversight that makes safe, high-quality research possible – evaluating participants for eligibility, directing the conduct of the trial, and ensuring every decision reflects both scientific rigor and genuine care for the people who trust us with their participation. You’ll also serve as a direct extension of the trusted patient-physician relationship that sits at the heart of our model: participants aren’t just enrollees, they’re patients, and they deserve a physician who treats them that way. This is a role for a physician who wants to be genuinely present in the work – one whose judgment, accountability, and commitment to patients directly shape the integrity and success of the research.

 

What You’ll Do

• Serve as the physician of record for clinical trials at an assigned site, assuming overall responsibility for the safe and compliant conduct of each study

• Evaluate participants for enrollment eligibility and monitor their safety, well-being, and response to therapy throughout their trial participation

• Ensure every participant is treated with respect and experiences the kind of thoughtful, patientcentered care that reflects Profound’s values

• Provide clinical leadership and oversight to the on-site research team, delegating responsibilities appropriately and keeping staff informed and aligned

• Maintain a thorough working knowledge of each protocol – including visit schedules, endpoint criteria, and investigational product requirements – and ensure the trial is conducted accordingly

• Oversee informed consent, adverse event documentation, and all required safety reporting to the sponsor and IRB

• Ensure data accuracy and completeness across case report forms and source documents, and support the site’s readiness for monitoring visits and audits

• Collaborate effectively with sponsors, the IRB, and the Profound Research team throughout the life of the trial

 

Requirements

 

 Essential Qualifications

• MD or DO with an active, unrestricted California medical license

• Prior experience conducting clinical research, with working knowledge of ICH/FDA/GCP guidelines and regulatory requirements • Proven ability to lead and collaborate with a multi-disciplinary clinical research team

• Strong communicator with patients, caregivers, clinical staff, and sponsor representatives

• High ethical standards, professional integrity, and a genuine passion for direct patient interaction

 

Preferred Qualifications 

• Established relationships with community physicians or patient populations in the San Diego area

• Familiarity with CTMS platforms and electronic data capture systems 

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Start Your Career in Clinical Research 

If you’re curious about how new treatments reach patients, detail-oriented by nature, and energized by work that genuinely matters – this is where that career begins.  

 

As an Assistant Clinical Research Coordinator at Profound Research, you’ll work alongside experienced clinical research staff at one of our sites, supporting the day-to-day execution of clinical trials that give patients access to therapies they couldn’t otherwise reach. You’ll learn by doing – gaining hands-on experience in study coordination, patient interaction, data collection, and clinical procedures – with a clear path to grow into greater ownership and responsibility over time.  

 

This isn’t a behind-the-desk role. You’ll be present with patients, part of a team, and contributing to research that has real-world impact from day one.  

 

What You’ll Do 

 

• Support the coordination of active clinical trials, including patient visits, scheduling, and study-related procedures 

• Assist with data collection and documentation, learning to apply the rigorous standards that clinical research demands 

• Perform and develop competency in clinical procedures including vital signs, EKGs, phlebotomy, and specimen processing 

• Interact directly with study participants – greeting them, explaining visit steps, and ensuring they feel supported throughout the process 

• Work closely with Clinical Research Coordinators and site leadership, asking questions, seeking feedback, and building your clinical knowledge base 

• Contribute to a compliant, audit-ready site by following established protocols, SOPs, and Good Documentation Practices 

 

What We’re Looking For 

You don’t need to have done this exact job before. You need to be the kind of person who takes ownership of their work, communicates clearly, pays close attention to detail, and genuinely cares about the patient experience. The rest we’ll help you build.  

 

• High school diploma or technical degree with 3+ years of relevant experience in life sciences, OR Associate’s degree with 1+ year of relevant experience, OR Bachelor’s degree with relevant coursework or experience in a clinical or life sciences setting 

• Familiarity with medical terminology and basic clinical procedures is a plus 

• Comfortable working in a fast-paced, team-based environment 

• Proficient with standard computer tools; able to learn new systems quickly 

• ICH-GCP and IATA certification required within a defined timeframe upon hire (we’ll support you through it) 

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

Start Your Career in Clinical Research 

If you’re curious about how new treatments reach patients, detail-oriented by nature, and energized by work that genuinely matters – this is where that career begins.  

 

As an Assistant Clinical Research Coordinator at Profound Research, you’ll work alongside experienced clinical research staff at one of our sites, supporting the day-to-day execution of clinical trials that give patients access to therapies they couldn’t otherwise reach. You’ll learn by doing – gaining hands-on experience in study coordination, patient interaction, data collection, and clinical procedures – with a clear path to grow into greater ownership and responsibility over time.  

 

This isn’t a behind-the-desk role. You’ll be present with patients, part of a team, and contributing to research that has real-world impact from day one.  

 

What You’ll Do 

 

• Support the coordination of active clinical trials, including patient visits, scheduling, and study-related procedures 

• Assist with data collection and documentation, learning to apply the rigorous standards that clinical research demands 

• Perform and develop competency in clinical procedures including vital signs, EKGs, phlebotomy, and specimen processing 

• Interact directly with study participants – greeting them, explaining visit steps, and ensuring they feel supported throughout the process 

• Work closely with Clinical Research Coordinators and site leadership, asking questions, seeking feedback, and building your clinical knowledge base 

• Contribute to a compliant, audit-ready site by following established protocols, SOPs, and Good Documentation Practices 

 

What We’re Looking For 

You don’t need to have done this exact job before. You need to be the kind of person who takes ownership of their work, communicates clearly, pays close attention to detail, and genuinely cares about the patient experience. The rest we’ll help you build.  

 

• High school diploma or technical degree with 3+ years of relevant experience in life sciences, OR Associate’s degree with 1+ year of relevant experience, OR Bachelor’s degree with relevant coursework or experience in a clinical or life sciences setting 

• Familiarity with medical terminology and basic clinical procedures is a plus 

• Comfortable working in a fast-paced, team-based environment 

• Proficient with standard computer tools; able to learn new systems quickly 

• ICH-GCP and IATA certification required within a defined timeframe upon hire (we’ll support you through it) 

\n

\n

Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization

About Profound Research 

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.  

 

Our Mission: Improving Lives by Providing Advanced Therapeutic Options 

 

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research 

 

Our Values:  

• Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered. 
• Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.  
• Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.  
• Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.  

We are committed to hiring dynamic, mission-driven leaders who operate with a strong sense of urgency to transform healthcare. Don’t see a position that fits? Join our Talent Network to get in touch and stay informed about opportunities.

 

Job Description

Join the Profound Research Talent Network

The Profound Research Talent Network is a way to get in touch with our team and be informed of opportunities within our growing portfolio that might be a match for you. Whether you're a clinician, clinical research professional, or recent graduate looking for your next opportunity, we want to hear from you.

 

Get to Know Us

 

Profound enables community physicians to offer clinical research as a therapeutic option to their patients. We provide all of the infrastructure, non-clinical services, and expertise need to provide patients access to the newest therapies available. Visit us at www.profoundresearch.io

 

 

We'd Like to Get to Know You

We are committed to hiring dynamic, mission-driven leaders who operate with a strong sense of urgency and want to make an outsized impact in healthcare. Common characteristics of the people who comprise Rubicon Founders and our portfolio companies:

 

Smart

Detail-oriented

Mission-driven

Entrepreneurial

Operates with urgency

 

Submit your resume and/or LinkedIn profile. If you look like a fit for one of our upcoming opportunities, a member of our Talent team will be in touch to schedule a conversation.

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Physical Requirements & Work Environment  

• This role is performed on-site at a clinical or office facility and requires prolonged periods of sitting, standing, or walking throughout the work environment 
• Requires the ability to communicate clearly in verbal and written forms and to read and interpret detailed materials
• Must be able to navigate a clinical facility, including areas with limited space, and transport supplies or work materials as needed
• May be required to wear personal protective equipment (PPE) in accordance with facility protocols
• Travel between company sites, meetings, or partner locations may be required
• Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role  

Why Join Profound Research?

• Meaningful Impact: Every role at Profound contributes to advancing medical knowledge and expanding therapeutic options for patients – the work we do here matters
• Professional Growth: We invest in our people through comprehensive training, certification support, and ongoing education to help you grow in your role and your career
• Leadership & Advancement: Profound is a place where initiative is recognized. We actively support internal growth and create pathways for people to take on greater responsibility over time
• Collaborative Culture: You’ll work alongside a team of dedicated professionals who are passionate about clinical research and committed to doing it well
• Full Benefits Package: Competitive compensation, health insurance, PTO, retirement plan, and professional development support
• Diverse Clinical Exposure: Work across multiple therapeutic areas and study phases, building a breadth of experience that’s rare in a single organization