Millwright Augusta, Georgia, United States, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biomanufacturing today.

We are seeking a highly motivated Millwright to assist with capital projects, recommissioning, startup, and maintenance activities. The ideal candidate will have expertise in mechanical systems including: pumps, hydraulics, rotating equipment, laser alignment, and mechanical seals. Familiarity with electrical systems is a plus. This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative applied to the various duties and aspects of the position. This person will be expected to play an integral part of Manus’ team located in Augusta, GA.

Why work at Manus Bio:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:

• Analyzes mechanical and operational problems on equipment. Takes necessary corrective actions to maintain equipment within proper operating specifications.
• Examines, tests and measures equipment for normal operation using gauges, instruments and records data on appropriate forms.
• Make preventive maintenance checks and inspections of equipment, reports findings to supervisor/team. Completes appropriate documentation and develops a follow-up action plan if required.
• Participates in required training and helps train new employees and retrain current employees within the assigned work area.
• Inspect new and used parts to determine proper tolerance, wear patterns, etc., using rules, calipers, micrometers, and other measuring instruments.
• Makes repairs necessary to maintain equipment per manufacturer specifications using hand tools and power tools. Must be able to operate hand tools in a safe and efficient manner.
• Operates lathe, drill press, grinder and other metalworking tools as required to make or repair parts.
• Must have computer skills that would enable them to create work orders, word documents and order parts through SAP.
• Comply with all documentation requirements regarding processing GMPs, safety, housekeeping, environmental and sanitation. All work must be done in compliance with company guidelines for safety and environment responsibility.
• Can operate within a team-based environment, willing to participate in team activities, serve in Leadership roles, and be receptive to receiving and giving constructive feedback to their team members and management.
• Must be able to follow detailed instructions as well as work in a safe and responsible manner.
• Must be able to function responsibly as part of a team.
• Must by physically able to handle equipment up to 50 kilograms using available equipment. Must be able to lift 40-pound containers repetitively. Must be able to wear required protective equipment, including respirators. Must be able to climb stairs and ladders repetitively when required.
• Work schedule will vary during shutdowns and other extraordinary conditions to include shift work.
• Must be able to follow minimal instructions and support safe work practices.

Required Qualifications:

• High School Diploma or GED.
• 5 years’ experience in the field of mechanical maintenance.
• Previous experience with hydraulics, rotating equipment, laser alignment, mechanical seals.
• Clear understanding and experience adhering to energy isolation/lockout tagout (LOTO) requirements.
• Possess strong communication (written & spoken) and interpersonal skills.
• Must be able to climb stairs and ladders when required.
• Execute the job function with minimal oversite.
• Must be able to wear required personal protective equipment (PPE).
• Experience with various computer applications in a Microsoft Windows environment.
• Work schedules may vary during outages, shutdowns, or other extraordinary conditions. This position must be able to provide support during these times.

Preferred Qualifications:

• Demonstrated ability to weld.
• Ability to troubleshoot using a model.
• Experience working in cGMP environments

Scientist II - High-Throughput Screening & Analytical Chemistry - Waltham, MA, Full-time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biotechnology today.

We are seeking a Scientist in Screening & Analytical Chemistry to lead development of high-throughput analytical workflows. This role focuses on method development for rapid, targeted metabolite quantification and integration with screening pipelines.

This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus’s research and development team located in Waltham, MA.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.

• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.

• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities

• Develop and optimize analytical methods for targeted metabolite quantification
• Lead method development on GC/MS, GC-FID, and LC-QQQ-MS platforms
• Design high-throughput analytical workflows with fast cycle times
• Develop sample preparation and derivatization strategies
• Work with automation and screening teams to support microtiter plate-based fermentations
• Analyze and interpret large datasets
• Mentor junior staff
• Interface with instrument vendors to maintain uptime and optimal performance
• Author SOPs and technical reports

Basic Qualifications

• PhD in Analytical Chemistry, Chemistry, or related field OR
• MS with 8+ years or BS with 13+ years relevant experience
• Strong experience in analytical method development

Required Technical Expertise

• GC-FID and GC/MS assay development for targeted quantitation and metabolite profiling
• LC/QQQ-MS assay develop for targeted quantitation
• Assay optimization for speed, sensitivity, and throughput

Preferred Experience

• Experience with high-throughput screening environments
• Integration of analytical workflows with automation
• Familiarity with liquid handling platforms
• Experience with LIMS (e.g. Benching) and large datasets
• Industrial biotech or applied R&D experience
• Experience with the following types of analytical instrumentation
  • UHPLC
  • GC-FID
  • GC/MS
  • LC/QQQ-MS
• Experience with a variety of sample extraction and preparation techniques, applying automated solutions when appropriate, from complex matrices
  • Microbial fermentation broth
  • Microbial biomass
  • Purified extracts

Maintenance Planning Engineer
Augusta, Georgia, United States, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self-motivated and highly organized individual for a position that will specialize in and lead all laboratory operations at our Boston BioFacility.

Why work at Manus Bio:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenges and hard work that comes with working on the cutting edge.

Responsibilities:

• Ensuring safety is the first goal of getting any task completed.
• Encouraging the execution of permits and use of all required PPE.
• Participating in PSSRs, risk assessments, and RCAs as needed.
• Maintain accurate SDS documentation for all lubricants and chemicals stored in maintenance.

• Plan maintenance activities across all Manus Bio facilities in Augusta, including but not limited to Sand 81, Fermentation, Utilities, and Waste Treatment.
• Develop preventative maintenance schedules according to specific machinery/unit operations. Create additional PMs for equipment that is not currently included. Set PM frequency per manufacturer requirements.
• Ensure that repairs and projects are done in a timely manner and meet the company’s expectations.
• Utilize MaintainX to coordinate planning, and interface with other stakeholders to implement features that will optimize workflow.
• Obtain and report weekly maintenance KPIs to management and adjust as needed.
• Schedule weekly planning meetings with the appropriate maintenance, utilities, and production personnel to finalize maintenance plans for the following week.
• Continued development of equipment BOM structure within MaintainX for all assets currently in use.
• When necessary or useful, propose and implement schemes or additional software to make planning more efficient.
• Demonstrate flexibility and creativity to shift activity and schedules with company demand.
• Expedite work orders and plan projects quickly with changing activity.

• Develop, plan and execute the annual Site Shutdown. Supervise maintenance activities according to the shutdown schedule and work closely with production on equipment downtime availability. This includes all necessary equipment inspections, including the following:
  • PRV and pressure vessels, back-flow preventors, and boilers/DAs.
• Organize internal maintenance projects and ensure work orders reflect the work being performed. Review all critical information with the appropriate personnel prior to performing the work.
• Develop strong working relationships with vendors/contractors and ensure that all contractor information is accurate in the contractor management system. This includes safety training, COI, and safety records.
• Maintain maintenance plans and review with designated crews for seamless execution.

• Ensure that all contracts on service agreements and inspections are updated accordingly. This includes services for the following equipment:
  • Air compressors, cranes and hoists, process dryers (suppression systems), site elevators, lift truck fleet, HVAC and chillers.
• Acquire any rental equipment necessary to support the production and maintenance departments. This includes but is not limited to the following:
  • HVAC, Dehumidifiers, scaffolding, lift trucks, cranes, compressors, and chillers.
• Perform all facility repairs as needed with the assistance of outside resources. This includes but is not limited to the following:
  • Underground repairs, clearing of drainage, roofing repairs, sheet metal, and demolition work.

• Obtain all POs prior to performing services or receiving materials/goods.
• Maintain a running list of all purchases made, and associated details.
• Receive all invoices in SAP to meet month-end deadlines.

• Maintain accurate documentation records per existing file structure. Some documents can also be saved on the associated work order in MaintainX for future reference. This includes but is not limited to the following:
  • Equipment, Instrumentation, service agreements, accounting (quotes, purchase orders, invoices), projects, safety (PSSRs, risk assessments, RCAs), and facility repairs.

Work Environment:

• Work is performed in an office and uncontrolled atmospheres. Exposure to harsh conditions—such as: dust, fumes, chemicals, hazardous materials, noise, and varying weather and temperatures—for short periods of time is possible. All employees are required to follow safety standards and wear all personal protective equipment in designated areas.
• While performing the duties of this position, the employee is regularly required to walk, stand, use hands and fingers, grip, handle or feel, reach with hands and arms, climb or balance, stoop, kneel, crouch or crawl, and talk and hear. The ability to lift and carry 10 pounds on a regular basis is required.

Required Qualifications:

• 0-5 years' experience in maintenance planning
• Excellent communication skills; both oral and written are required.
• Strong analytical and problem-solving skills are required.
• Computer skills and an in-depth knowledge of Microsoft Windows based programs are required.
• Ability to work flexible hours.
• Requires effective time management skills, personal conduct, and change management abilities.
• Ability to effectively interact with co-workers, vendors, contractors and other business contacts.
• Must comply with Manus Bio’s core values for the safe and efficient operation of the business and maintaining sound relationships among and with employees.

Preferred Qualifications:

• Experience working in cGMP environments.
• Experience working with CMMS systems (SAP, FIIX, etc.)
• Proficiency in utilizing Microsoft applications (word, excel, power point, etc.)
• Experience in biochemical, petrochemical, pharmaceutical, energy, oil and gas industries are preferred.

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

The Chemical/Fermentation Plant Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance, equipment reliability, and operations. Creativity and decision-making skills are required. Must be able to maintain a good working relationship with all personnel. Work as a member of the fermentation plant team which includes assisting in the Pilot Plant. Controls, monitors, and measures fermentation processes as instructed. Abides by all safely, environmental, and quality requirements. Perform minor maintenance and duties related to product testing, including sampling.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities:

Interface with production to provide resources to solve fermentation and product isolation problems. Execute and help evaluate fermentation experiments. This activity includes:

• Prepare fermentation and downstream equipment in accordance to SOPs, this include equipment setup, media make up, equipment disassembly, cleaning, etc.
• Collect samples during manufacturing process for analytical analysis.
• Prepare all required batch records, reflect constantly changing experimental designs and ensure clear communication to the process development subject matter expert of the targeted design parameters.
• Collect and review all batch records. Data reduction includes electronic data conversion into and formatting in Excel for purposes of trending key operational parameters. Data is reviewed and checked. Off-line analytical data is reviewed for accuracy, retesting if necessary. Final results are organized and distributed to the process development subject matter expert.
• Coordinate day-to-day Fermentation Plant activities, including manufacturing scheduling conflicts, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
• Prepare SOP for new process or operations as needed.
• Assist and provide hands-on support of Fermentation Plant maintenance activities, including rebuilding of probes and housings, changing out gear boxes on vessels, rebuilding valves, piping modifications, and modifying/fabricating new and existing equipment.
• Maintain the upkeep of the Fermentation Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; Use your own tools to correct minor maintenance issues is encouraged.
• Adhere to company EH&S policies and procedure. Ensure fermentation plant compliance with safety and environmental regulations.
• Physical demand requirements are in excess of sedentary work due to inspection of equipment. Must be able to climb stairs and ladders.
• Must be able to wear required protective equipment including respirators (if needed).
• Work schedule is considered day shift but will vary depending on manufacturing plan and other extraordinary conditions.
• Ensure Fermentation plant compliance with safety and environmental regulations.

Required Qualifications:

• High school diploma or GED equivalent.
• Minimum of 3 years fermentation or related plant operator experience.
• Must be able to follow minimal instructions and support safe work practices.

• Must be an excellent team member with strong communication skills and a desire to work collaboratively.
• Must be flexible with day-to-day duties and able to thrive in a start-up environment.
• Must hold themselves to the highest professional and ethical standards.
• Familiar with the production fermentation and downstream processes and equipment as well as microbiological and analytical laboratory procedures.
• Demonstrates flexibility in job rotations/various assignments.
• Basic PC skills which include Windows, Microsoft Office.

Preferred Qualification and Working Style:

• SAP skills
• Certified Train the Trainer skills
• Delta V controls experience

Job Type: Regular, Full-Time

Employee Status: Permanent

Sales Manager - LATAM Remote, Full-Time (MUST LIVE IN MEXICO)

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a highly motivated Sales Manager to manage a portfolio of regional accounts. The primary accountability of this position is to profitably grow sales by providing unparalleled customer service and quality products. This sales professional will be focused on identifying customer’s unmet needs to obtain new business, arranging client presentations, strengthening relationships at multiple levels within the customer’s organization and successfully negotiating supply contracts.

This position supports the commercial sales activities of products using technical, scientific, and customer knowledge to influence customers in applying the products/services to their formulations/ applications resulting in revenue generation.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Major Responsibilities

• Maintaining and profitably growing sales to a regional portfolio of customers.
• Developing account plans in line with the customers’ strategies, inclusive of ambitious growth targets and innovation opportunities.
• Utilizing our Technical Service, Marketing resources team to develop strong customer relationships.
• Develop and deliver sales presentations and close sales.
• Quantify and articulate the current and potential value created for the customer; and identify opportunities to solve customer problems with existing products or new requirements.
• Assist with the development of new products and expand existing business with our formulated products.
• Providing an accurate forecast of customers’ sales volumes and revenues. Maintaining a monthly dashboard and activity report.
• Generating new business by finding opportunities and converting them into revenue. Growing the “pipeline” for the customer portfolio to ensure reliable stream of future new business. Provide sales forecasts, sales planning, and CRM in an effective timely manner.
• Negotiating supply contracts with customers and handling the day-to-day management of the account.
• Working with customers’ procurement, R&D, marketing, management, and other buying influencers to sell ingredients and achieve revenue and profit targets for the company.
• Be tuned in to customer issues and employ problem solving tactics to obtain successful solutions and total customer satisfaction.
• Attend trade shows and represent Manus Inc. in a professional manner.

Position Qualification

• A bachelor’s degree in food science, Business, or related field with minimum of 5 years of sales experience.
• Consistent track record of managing and penetrating complex accounts and delivering results to processors/manufacturers in the food industry.
• Validated negotiation skills and strong organizational and time management skills.
• Demonstrated ability to build and use strong relationships to generate sales & profitability.
• Demonstrated ability to successfully coordinate many complex activities / projects simultaneously.
• Solid presentation skills and excellent written and oral interpersonal skills.
• Technical knowledge of sweetener formulation.
• Strong analytical, problem solving, and negotiation skills.
• Organization and use of CRM database systems.
• Ability to travel at least 50% of the time
• Excellent organizational, planning, and prioritization skills.

Industrial PainterAugusta, Georgia, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a skilled and detail-oriented Industrial Painter to join our team. The successful candidate will be responsible for preparing surfaces, applying paints and coatings, and ensuring high-quality finish on industrial equipment, structures, and surfaces. This role requires knowledge of various painting techniques, safety standards, and the ability to work in diverse environments.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenges and hard work that comes with working on the cutting edge.

Responsibilities:

• Prepare surfaces for painting by cleaning, sanding, and applying primers or sealants.
• Mix and apply paints, coatings, and finishes using brushes, rollers, or spray equipment.
• Interpret blueprints, drawings, and specifications to determine painting requirements.
• Operate and maintain painting tools and equipment, including spray guns, compressors, and scaffolding.
• Ensure proper ventilation and safety measures are in place during painting operations.
• Inspect finished surfaces for quality and touch up as needed.
• Maintain a clean and organized work area.
• Follow all safety protocols and environmental regulations.

Qualifications:

• High school diploma or equivalent; vocational training in painting or a related field is a plus.
• Proven experience as an industrial painter or similar role.
• Familiarity with painting techniques, surface preparation, and coating types.
• Ability to work at heights and in confined spaces.
• Strong attention to detail and commitment to quality.
• Physical stamina and manual dexterity.
• Knowledge of safety procedures and hazardous materials handling.

Preferred Skills:

• Certification in industrial painting or coating application (e.g., NACE, SSPC).
• Experience with abrasive blasting or powder coating.
• Forklift or aerial lift certification.

Working Conditions:

• Exposure to fumes, chemicals, and varying temperatures.
• Use of personal protective equipment (PPE) is required.
• May involve working in noisy, dusty, or outdoor environments.

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a highly motivated Process Engineer to support manufacturing operations. This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative applied to the various duties and aspects of the position. This person will be expected to play an integral part of the company’s operations team.

Why work for the Company:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:

Provides day-to-day process monitoring, including troubleshooting of process, yield, quality and equipment reliability issues.

• Develops and maintains plant material balances, capacity evaluations, and area/plant yields. Reports on critical items through KPIs.
• Scale up R&D equipment and processes to improve yields and cycle time on new processes.
• Engage with product marketing and manufacturing groups for process requirements.
• Collaborate with manufacturing to ensure equipment can be reliable and meet quality and cost targets. This activity includes design for enhancements to existing equipment manufacturability and new product equipment.
• Identifies, develops and implements process capacity and efficiency (yield) improvements, including operator tracking and downtime data and leading technical improvement teams.
• Develops and maintains area process sample schedules and provides coordination with lab.
• Performs execution and documentation of plant trials including detailed material balances and evaluation of in-process quality and batch record data.
• Monitors equipment performance and in-use time and coordinates production issues with the appropriate personnel.
• Completes investigations and Corrective Action Reports for technical processing issues.
• Initiates/supports area capital projects, including scope development, cost justification, control logic and start-up support. Take part in project teams as Leader, technical expert or operational expert.
• Perform as equipment and/or technology owner or expert to support operation and train operators.
• Provides Process Safety Management ownership responsibilities including process hazard analysis participation, supporting upkeep of drawings, procedures, and PSI files, and sponsoring management of change for equipment and process changes.
• Supports site safety and quality initiatives through participation & leadership in teams, incident/CAR analysis, and follow-up.
• Ensures smooth integration of activities and effective teamwork within Site Engineering functions (between project engineering, process engineering, and process controls engineering teams).

Required Qualifications:

• B.S. in Chemical Engineering/Chemistry or a related discipline
• Minimum three to eight years’ experience in a chemical or pharmaceutical plant environment.
• Knowledge of piping and valve operations to control processes.
• Familiar with and capable of generating engineering flow diagrams, process flow diagrams, and capacity analysis.
• Good understanding of analytical techniques (GC) and fermentation bioprocess is desirable.
• Experience in food or pharma industry desired

Preferred Working Style:

• Must be fully responsible and accountable for compliance with the provision of the safety, health, and environmental (SHE) policies
• Must comply with Good Laboratory Practice and current Good Manufacturing Practice
• Must be very well-organized and be able to handle multiple projects simultaneously
• Must be a quick learner who is self-motivated and able to ask questions and seek clarity
• Must be flexible with day-to-day duties and able to thrive in a start-up environment
• Must be an excellent team member with strong communication skills and a desire to work collaboratively
• Must hold him or herself to the highest professional, scientific and ethical standards

Position Summary

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

The Senior Mechanical Designer is responsible for the design, development, and documentation of mechanical systems, equipment, and facilities used in biotech and pharmaceutical manufacturing environments. Working within a cross-functional engineering team, this role drives projects from concept through installation, ensuring all designs comply with GMP regulations, FDA guidelines, and applicable industry standards. The ideal candidate brings deep AutoCAD and AutoCAD 3D proficiency, a strong mechanical foundation, and a proven track record in a regulated manufacturing setting.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Key Responsibilities

Design & Engineering

• Develop detailed 2D and 3D mechanical drawings, models, and assemblies using AutoCAD and AutoCAD 3D in compliance with GMP and cGMP standards.
• Design process equipment, piping systems, utility systems, and facility modifications for biotech/pharma manufacturing areas.
• Produce and maintain engineering documentation including P&IDs, equipment layouts, installation drawings, BOMs, and design specifications.
• Perform design calculations, tolerance analyses, and material selections appropriate for cleanroom and regulated environments.
• Review and redline vendor drawings; ensure equipment meets functional and regulatory requirements.

Project Execution

• Lead mechanical design workstreams on capital projects from initiation through commissioning, qualification (IQ/OQ), and handover.
• Collaborate with process engineers, automation engineers, quality, and facilities to align mechanical designs with operational requirements.
• Support equipment procurement by developing RFQs, evaluating vendor proposals, and participating in FATs/SATs.
• Coordinate with contractors and construction teams during installation; provide field engineering support as needed.
• Track design deliverables, manage drawing revisions, and maintain controlled document packages in accordance with change control procedures.

Compliance & Quality

• Ensure all mechanical designs adhere to FDA 21 CFR Part 210/211, EU GMP Annex 1 (where applicable), ASME BPE, and other relevant standards.
• Participate in design reviews, HAZOP studies, and risk assessments; document findings and drive closure of action items.
• Support change control, deviation management, and CAPA processes from an engineering design perspective.
• Maintain drawing and document archives in the company engineering document management system (EDMS).

Mentorship & Collaboration

• Provide technical guidance and mentorship to junior and mid-level mechanical designers.
• Contribute to CAD standards, drawing templates, and best-practice documentation for the engineering team.
• Actively participate in cross-functional project teams and present design solutions to stakeholders at all levels.

Qualifications

Required

• Bachelor’s degree in Mechanical Engineering, Mechanical Design Technology, or related field
• 7+ years of mechanical design experience, with at least 3 years in a GMP-regulated biotech or pharma environment
• Advanced proficiency in AutoCAD 2D and AutoCAD 3D (AutoCAD Mechanical or Plant 3D experience a plus)
• Demonstrated experience designing process equipment, utility systems, or facility improvements in a manufacturing plant
• Proficiency in engineering calculations, GD&T, and material selection for sanitary/pharmaceutical applications
• Strong written and verbal communication skills; ability to produce clear technical documentation

Preferred

• Experience with ASME BPE piping standards and hygienic design principles
• Familiarity with cleanroom classifications (ISO 5–8) and HVAC/environmental control concepts
• Experience with SOLIDWORKS or Inventor as a supplemental tool
• Knowledge of CFR 21 Part 11 electronic records requirements
• PMP or equivalent project management certification
• Lean / Six Sigma Green Belt or equivalent continuous improvement experience

Work Environment & Physical Requirements

• Work is performed in a combination of office/CAD environment and active manufacturing/lab areas including cleanrooms.
• Occasional gowning required when entering classified manufacturing spaces; adherence to site EHS and GMP protocols is mandatory.
• May require occasional travel to vendor sites for FATs or to other company facilities.
• Ability to lift up to 25 lbs and stand/walk on the production floor for extended periods during project support activities.

Position Summary

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

The Mechanical Designer supports the design, development, and documentation of mechanical systems, equipment, and facilities used in biotech and pharmaceutical manufacturing environments. Working under the direction of senior engineers and project leads, this role contributes to projects from concept through installation, ensuring designs comply with GMP regulations, FDA guidelines, and applicable industry standards. The ideal candidate brings solid AutoCAD and AutoCAD 3D proficiency, a foundational mechanical background, and an eagerness to grow within a regulated manufacturing setting.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Key Responsibilities

Design & Engineering

• Develop 2D and 3D mechanical drawings, models, and assemblies using AutoCAD and AutoCAD 3D in compliance with GMP and cGMP standards.
• Assist in the design of process equipment, piping systems, utility systems, and facility modifications for biotech/pharma manufacturing areas.
• Produce and maintain engineering documentation including P&IDs, equipment layouts, installation drawings, BOMs, and design specifications.
• Support design calculations, tolerance analyses, and material selections appropriate for cleanroom and regulated environments.
• Review vendor drawings under guidance from senior staff; help verify equipment meets functional and regulatory requirements.

Project Execution

• Support mechanical design workstreams on capital projects from initiation through commissioning and qualification (IQ/OQ).
• Collaborate with process engineers, automation engineers, quality, and facilities to ensure mechanical designs align with operational requirements.
• Assist with equipment procurement activities including RFQ preparation and participation in FATs/SATs.
• Coordinate with contractors and construction teams during installation; provide field support as directed.
• Track design deliverables, manage drawing revisions, and maintain controlled document packages in accordance with change control procedures.

Compliance & Quality

• Ensure all mechanical designs adhere to FDA 21 CFR Part 210/211, ASME BPE, and other relevant standards under guidance from senior staff.
• Participate in design reviews and risk assessments; document findings and follow up on assigned action items.
• Support change control and deviation management processes from an engineering design perspective.
• Maintain drawing and document archives in the company engineering document management system (EDMS).

Collaboration

• Work closely with senior designers and engineers to develop technical skills and understanding of GMP design principles.
• Follow established CAD standards, drawing templates, and best-practice documentation for the engineering team.
• Participate actively in cross-functional project teams and communicate design status to team members and stakeholders.

Qualifications

Required

• Associate’s or Bachelor’s degree in Mechanical Engineering Technology, Mechanical Design, or related field
• 2–5 years of mechanical design experience; entry-level candidates with strong internship or co-op experience will be considered
• Proficiency in AutoCAD 2D and AutoCAD 3D; ability to produce accurate, complete design packages independently
• Basic understanding of GMP requirements and design documentation practices in a regulated environment
• Working knowledge of GD&T, engineering calculations, and material selection
• Strong attention to detail and ability to manage multiple drawing deliverables concurrently

Preferred

• Experience in a GMP-regulated biotech or pharmaceutical manufacturing environment
• Familiarity with ASME BPE piping standards and hygienic design principles
• Exposure to cleanroom classifications (ISO 5–8) and HVAC/environmental control concepts
• Experience with SOLIDWORKS or Inventor as a supplemental tool
• Familiarity with engineering document management systems (EDMS)
• Lean / continuous improvement mindset or coursework

Work Environment & Physical Requirements

• Work is performed in a combination of office/CAD environment and active manufacturing/lab areas including cleanrooms.
• Occasional gowning required when entering classified manufacturing spaces; adherence to site EHS and GMP protocols is mandatory.
• May require occasional travel to vendor sites for FATs or to other company facilities.
• Ability to lift up to 25 lbs and stand/walk on the production floor for extended periods during project support activities.

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

The Senior Process Controls Engineer serves as a technical leader and subject matter expert for all automation, process control, and instrumentation systems across the Manus Augusta BioFacility. This role is responsible for the full lifecycle of control system projects – from design and configuration through commissioning and continuous improvement – while also providing advanced technical support to Production operations. The Senior Process Controls Engineer mentors junior controls engineers and technicians, leads complex troubleshooting efforts, and partners cross-functionally with Engineering, Manufacturing, Quality, and EHS to deliver reliable, safe, and compliant automation solutions.

Why work at Manus:

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:

Technical Leadership & Advanced Engineering

• Serve as site SME for process control systems, including PLC, DCS, HMI, SCADA, and associated instrumentation; provide authoritative guidance to engineering and operations teams.
• Lead the design, configuration, testing, and commissioning of complex control systems for new and modified processes, ensuring integration with upstream and downstream operations.
• Evaluate and select control hardware and software platforms; develop and enforce site-wide standards for control architecture, programming conventions, and documentation.
• Lead advanced troubleshooting of process control issues; perform root cause analysis (RCA) and drive implementation of permanent corrective and preventive actions (CAPA).

Project Management & Capital Support

• Own and lead area capital projects from scope development and cost justification through control logic design, factory acceptance testing (FAT), and site commissioning.
• Develop project plans, manage timelines, coordinate contractor and vendor activities, and communicate project status to engineering and site leadership.
• Review and approve engineering deliverables including P&IDs, control narratives, cause-and-effect matrices, functional specifications, and as-built documentation.
• Mentor and guide Process Controls Engineer I/II staff on project execution and technical best practices.

Production Support & Continuous Improvement

• Provide senior-level technical support to Production for control system configuration, process control parameter changes, and process troubleshooting across multiple systems.
• Partner with Production and Process Development to identify and implement improvements in automation, efficiency, data collection, and reporting.
• Champion and lead continuous improvement initiatives that reduce downtime, improve process reliability, and increase overall equipment effectiveness (OEE).
• Analyze process and historian data to identify control performance gaps and recommend enhancements to control strategies.

Training, Documentation & Compliance

• Develop, maintain, and deliver training programs for console operators on automated systems, including training materials and process simulation tools.
• Ensure all control system work and documentation adheres to site GMP guidelines, change control procedures, and applicable regulatory standards.
• Support site safety and quality initiatives through active participation and leadership in incident investigations, CAR analysis, and follow-up actions.
• Maintain accurate and complete documentation in accordance with good documentation practices (GDP) and site quality management systems.

Qualifications:

• Bachelor’s degree in Engineering (Chemical, Electrical, Mechanical, or related discipline).
• Minimum 5–7 years of progressive experience in process controls or automation engineering in a manufacturing environment; biotech, pharmaceutical, or specialty chemical experience strongly preferred.
• Minimum 5-7 years of progressive experience in Project Management responsibilities
• Demonstrated hands-on expertise with PLC and/or DCS platforms (e.g., Rockwell, Siemens, Emerson DeltaV, Honeywell) including programming, configuration, and commissioning.
• Proven experience leading capital projects, including scope development, cost estimation, and site commissioning.
• Strong knowledge of process instrumentation (flow, pressure, temperature, level, analytical) and control loop tuning.
• Solid understanding of safety, health, environmental, quality systems, and GMP regulatory compliance requirements.
• Excellent verbal and written communication skills with the ability to present technical content to both technical and non-technical audiences.
• Strong analytical and problem-solving skills; demonstrated ability to lead RCA investigations and implement lasting solutions.
• Physical ability to perform equipment inspection and troubleshooting in a manufacturing environment, including climbing stairs and ladders and wearing required PPE.
• Work schedule flexibility during shutdowns and other extraordinary operational conditions.

Preferred Qualifications:

• Experience with bioprocess automation, fermentation systems, or BioFacility environments.
• Proficiency with SCADA systems, historian platforms (e.g., OSIsoft PI), and MES integration.
• Familiarity with ISA-88 batch control standards and ISA-99/IEC 62443 cybersecurity standards for industrial control systems.
• Knowledge of 21 CFR Part 11 requirements for electronic records and electronic signatures in a GMP setting.
• Experience with process simulation tools and operator training systems (OTS).
• Professional Engineer (PE) license or pursuit thereof.
• Prior experience mentoring or leading junior engineering staff.

Core Competencies:

• Controls and Automation expertise
• Project Leadership
• Analytical thinking & RCA
• Cross-functional collaboration
• GMP & Regulatory acumen
• Mentorship & knowledge sharing
• Continuous improvement mindset
• Clear technical communication