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Senior Associate Scientist, Viral Vector Cell Line Development (Contractor)
Asimov · Boston, Massachusetts, United States
$55–60/hr
100 days ago
♡
Research Associate, Cell Line Development (Contractor)
Asimov · Boston, Massachusetts, United States
$30–35/hr
102 days ago
♡
Principal Scientist, Biologics Cell Line Development
Asimov · Boston, Massachusetts, United States
$170k–190k
194 days ago
♡
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Senior Associate Scientist, Viral Vector Cell Line Development (Contractor)
Asimov · Boston, Massachusetts, United States
Pay
$55–60/hr
Setting
On-site
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We're seeking a Senior Associate Scientist to join our Synthetic Biology team on a 6 month contract. The ideal candidate will have a proven track record performing AAV and/or lentiviral vector stable producer cell line development in an industry setting. They will be a key contributor to our team, participating in the creation of stable producer cell lines for AAV and/or lentiviral vector therapeutics and research projects to improve our cell line development workflows. They will also work closely with Asimov’s synthetic biology and process development teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role:
Perform AAV and/or lentiviral vector stable producer cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment
Perform biological assays including ddPCR, ELISA, and flow cytometry
Support innovation through development of novel workflows and applications
Support research projects to develop viral vector therapeutics with enhanced quality attributes such as empty/full ratio, potency and/or cell targeting
Work effectively as part of a cross-functional team in support of a synthetic biology design platform
Design experiments, analyze data, troubleshoot, and maintain detailed records
Represent the cell line development function on project teams, making decisions for cell line activities and effectively communicating results, progress and plans
This is a full-time, 6-month contract position providing maternity leave coverage. While the role is intended to support this temporary need, there may be an opportunity to extend the contract or transition to a permanent position based on business needs.
About You:
B.S or M.S. in Biological Engineering, Virology, Cell Biology, Molecular Biology, or a related field
5+ years of hands-on experience in AAV and/or lentiviral vector producer cell line development in support of GMP production of cell or gene therapies
Experience performing transfections, viral transductions, flow cytometry, and quantitative gene expression analyses (ddPCR, qPCR, ELISA) is highly desired
Experience with viral genome engineering, and/or host cell genome engineering related to virus production or producer cell line technologies is highly desired
Strong written and verbal communication skills required
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Listed by Asimov for a position based in the United States. Employers on this board attest they are hiring domestically.
Research Associate, Cell Line Development (Contractor)
Asimov · Boston, Massachusetts, United States
Pay
$30–35/hr
Setting
On-site
Research Associate, Cell Line Development (Contractor)
Location
Boston, MA
Employment Type
Contract
Department
Cell Line Development
Compensation
$30 – $35 per hour
Overview
Application
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We are seeking a Research Associate to join our Cell Line Development team on a 6 month contract to help push the boundaries of biotherapeutic cell line development. In this role, you will conduct CHO-based cell line engineering and screening to produce human therapeutics. In addition, you will execute synthetic biology studies and new technology evaluations to continuously innovate our workflows and expression platform. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role:
Perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
Complete comprehensive documentation of studies in an Electronic Lab Notebook (ELN).
Work with scientists to optimize workflows across clone screening, transfection, small-scale assays, and product quality assessment.
Contribute to innovation focused on the development of novel cell line development workflows and applications.
This role will begin as a full-time, 6 month contract. Dependent on business needs, there is potential for the contract to be extended or converted into a permanent position.
About You:
You have a bachelor’s or master’s degree in Biological Engineering, Cell Biology, Molecular Biology, Chemical Engineering or a related field.
You have at least 1 year experience culturing mammalian cells.
Being detail-oriented isn’t just a sound bite for you, it’s part of your DNA. Keeping track of a bunch of moving parts is easy for you because you’re highly organized. It’s not your first time following a standardized workflow or pipeline.
You value teamwork and are motivated to contribute to the team’s goals. Working as part of a highly integrated research team is exciting to you.
You’re a creative problem solver and get excited about the opportunity to drive the creation of industry-disruptive technology.
Don’t let this stop you from applying, but it’s a plus if you are familiar with transfections, antibody/protein expression, cell culture liquid handling automation, ambr bioreactors, and/or ddPCR.
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
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Listed by Asimov for a position based in the United States. Employers on this board attest they are hiring domestically.
Principal Scientist, Biologics Cell Line Development
Asimov · Boston, Massachusetts, United States
Pay
$170k–190k
Setting
On-site
Principal Scientist, Biologics Cell Line Development
Location
Boston, MA
Employment Type
Full time
Department
Cell Line Development
Compensation
$170K – $190K
The base salary hiring range is $170,000 to $190,000 annually. The base salary offered may vary based on factors such as the final candidate’s relevant knowledge, skills and experience for the role. Our total rewards package also includes the opportunity for stock options, eligibility for our 401(k) plan, medical, dental, vision, life and disability insurances, as well as a career development stipend. Our robust time-off policy includes flexible time-off and unlimited sick time. We will talk about compensation in our first conversation and be transparent throughout the process about which level we think is the best match for you in our organization.
Overview
Application
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We are seeking a Principal Scientist to join our Biologics Cell Line Development team in Boston, MA and help push the boundaries of biotherapeutic cell line development. This role is for a scientific innovator and a manager of junior scientists. The successful candidate will conduct & supervise CHO-based cell line development for biologic therapeutics moving into clinical development. Significant effort designing complex experimental approaches to improve expression systems and workflows through innovation and implementation of new technology is also an important part of this role.
The successful candidate will also work cross-functionally with Asimov’s synthetic biology, modeling, process development and analytical teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role:
You’ll perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
You’ll drive innovation through the development of improved genetic components, host cell line engineering and cell line development process optimization.
You’ll identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation.
You’ll represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress and plans.
You’ll represent Asimov externally, contributing to industry conferences, industry forums, filing patents, and publishing peer-reviewed manuscripts.
You’ll manage and mentor a team of 3+ scientists focused on CHO-based biologics CLD, providing technical direction and supporting them in their professional development.
About You:
8+ years of experience in CHO-based cell line development is a must, stemming from expressing IgGs and bispecifics in an industrial CLD environment.
You have a Ph.D. in Biological Engineering, Cell Biology, Molecular Biology, or a related field.
You’re a creative problem solver never satisfied with the status quo and get excited about the opportunity to drive the creation of disruptive technology.
Minimum 1 year experience managing direct report(s) and providing technical guidance.
Don’t let this stop you from applying, but it’s a plus if you are familiar with any of the following: vector optimization to improve titer and product quality attributes for complex bispecific scaffolds; CLD process optimization; or development of automated high-throughput screening for CLD workflows.
Experience working with a global customer base isn’t a requirement for this role but bonus points if you have it.
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Apply for this Job
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Listed by Asimov for a position based in the United States. Employers on this board attest they are hiring domestically.
Senior Scientist, Biologics Cell Line Development
Asimov · Boston, Massachusetts, United States
Pay
$145k–165k
Setting
On-site
Senior Scientist, Biologics Cell Line Development
Location
Boston, MA
Employment Type
Full time
Department
Cell Line Development
Compensation
$145K – $165K
The base salary hiring range is expected to be $145,000 to $165,000 annually. The base salary offered may vary based on factors such as the final candidate’s relevant knowledge, skills and experience for the role. Our total rewards package also includes the opportunity for stock options, eligibility for our 401(k) plan, medical, dental, vision, life and disability insurances, as well as a career development stipend. Our robust time-off policy includes flexible time-off and unlimited sick time. We will talk about compensation in our first conversation and be transparent throughout the process about which level we think is the best match for you in our organization.
Overview
Application
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We are seeking a Senior Scientist to join our Biologics Cell Line Development team in Boston, MA and help push the boundaries of biotherapeutic cell line development. This role is for a scientific innovator and a manager of junior scientists. The successful candidate will conduct & supervise CHO-based cell line development for biologic therapeutics moving into clinical development. Significant effort designing complex experimental approaches to improve expression systems and workflows through innovation and implementation of new technology is also an important part of this role.
The successful candidate will also work cross-functionally with Asimov’s synthetic biology, modeling, process development and analytical teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role:
You’ll perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
You’ll drive innovation through the development of improved genetic components, host cell line engineering and cell line development process optimization.
You’ll identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation.
You’ll represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress and plans.
You’ll represent Asimov externally, contributing to industry conferences, industry forums, filing patents, and publishing peer-reviewed manuscripts.
You’ll manage and mentor a team of 3+ scientists focused on CHO-based biologics CLD, providing technical direction and supporting them in their professional development.
About You:
5+ years of experience in CHO-based cell line development is a must, stemming from expressing IgGs and bispecifics in an industrial CLD environment.
You have a Ph.D. in Biological Engineering, Cell Biology, Molecular Biology, or a related field.
You’re a creative problem solver never satisfied with the status quo and get excited about the opportunity to drive the creation of disruptive technology.
Minimum 1 year experience managing direct report(s) and providing technical guidance.
Don’t let this stop you from applying, but it’s a plus if you are familiar with any of the following: vector optimization to improve titer and product quality attributes for complex bispecific scaffolds; CLD process optimization; or development of automated high-throughput screening for CLD workflows.
Experience working with a global customer base isn’t a requirement for this role but bonus points if you have it.
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Apply for this Job
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Listed by Asimov for a position based in the United States. Employers on this board attest they are hiring domestically.
Staff Software Engineer
Asimov · Boston, Massachusetts, United States
Pay
$179k–230k
Setting
Hybrid
Staff Software Engineer
Location
Boston, MA
Employment Type
Full time
Location Type
Hybrid
Department
Software
Compensation
$179K – $230K
The base salary hiring range for this position is expected to be $179,000 to $230,000 annually. The base salary offered may vary based on factors such as the final candidate’s relevant knowledge, skills and experience for the role. Our total rewards package also includes the opportunity for stock options, eligibility for our 401(k) plan, annual career development stipend, medical, dental, vision, life and disability insurances. Our robust time-off policy includes flexible time-off and unlimited sick time. We will talk about compensation in our first conversation and be transparent throughout the process about which level we think is the best match for you in our organization
Overview
Application
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
What would software engineering be like without an IDE? How could humans design a modern plane without CAD? Genetic engineering will be even more demanding—and we're building the tools to make it possible. Kernel is our platform for bioengineers to design, build, and debug genetic systems as confidently as we ship code. We're looking for a Staff Software Engineer to help us build it.
You'll join an interdisciplinary team that works directly with scientists, synthetic biologists, and computational biologists alongside your teammates in software engineering and product.
About the Role:
Make architectural decisions that will shape Kernel for years, with real ownership over how the system evolves.
Design GraphQL APIs for searching, editing and analyzing tens of thousands of genetic constructs using Python 3, SQLAlchemy and Strawberry.
Architect data models that represent the genuine complexity of biological systems.
Interface directly with synthetic biologists to understand their workflows and identify tools that would transform their productivity.
Be part of an on-call rotation to support the software you’ve helped develop.
About You:
You have 10+ years building production software - systems that other engineers depend on, not research code that runs once.
You have deep expertise in Python 3, and ideally with GraphQL, SQLAlchemy, and/or Strawberry.
You’re the kind of engineer who loses track of time working on an interesting technical problem. You want challenges that will have you waking up with a new idea that you can’t wait to try.
You think about API design, data migrations, and what happens when the system has 10x usage.
You want to help design a product with a close-knit team, not just write code from predefined specifications. You can navigate the ambiguity of building something first-of-its-kind.
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Apply for this Job
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Listed by Asimov for a position based in the United States. Employers on this board attest they are hiring domestically.
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