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(Senior) Research Associate, Stem Cell Biology
Conception · Berkeley, California, USA
Pay
$75k–200k
Setting
On-site
About Conception
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, and reproductive biology to make this vision a reality.
The position
We are seeking an extremely hard-working, highly skilled, hands-on scientist or scientific specialist to support our pluripotent stem cell program. This is a technical specialist role for someone who wants to be in the lab doing difficult, delicate, high-impact work.
Ideally, you have direct experience deriving, establishing, expanding, banking, and characterizing pluripotent stem cell lines. We are looking for a rigorous bench scientist who is excited to execute, troubleshoot, repeat, improve, and master technically demanding workflows. The right person will be flexible in focus, willing to learn new techniques, and motivated to contribute wherever the lab needs them most. Experience with QC readout establishment, stem cell differentiation, 3D culture, or related reproductive biology techniques is highly valuable.
Title is negotiable based on experience and may range from Scientific Specialist to Senior Scientist.
What you’ll do
- Build, optimize, and repeatedly execute workflows needed for stem-cell-derived reproductive cell development
- Derive, establish, expand, bank, and characterize iPSC & ESC lines
- Maintain high-quality ESC/iPSC cultures, document passage history and culture conditions, and support characterization and QC assays
- Troubleshoot protocols, improve reproducibility, and help maintain consistency across difficult and delicate workflows
- Establish epigenetic quality readouts
- Collaborate closely with stem cell, reproductive biology, embryology, genomics, and preclinical teams
- Execute technically demanding workflows with precision, timing, repetition, and consistency
What we’re looking for
- PhD in stem cell biology, developmental biology, reproductive biology, cell biology, embryology, bioengineering, or a related field
- Ideally 4+ years of hands-on experience with human pluripotent stem cell culture, reproductive biology, or related technical workflows
- Direct experience with ESC/iPSC derivation, or ESC/iPSC line establishment is especially valuable
- Strong aseptic technique and experience maintaining sensitive, high-value cell lines
- Excellent attention to detail, reliability, and comfort with difficult, repetitive protocols that require precision and consistency
- Hands-on experience with ESC/iPSC expansion and banking, stem cell QC, 3D culture, organoid culture, co-culture systems, microdissection, micromanipulation, or long-duration tissue and cell culture workflows is highly desirable
- Strong work ethic and team-first mindset. Willing to do hands-on work, including routine and repetitive tasks, and step in wherever needed
- Able to thrive in a high-intensity, fast-paced, flexible startup environment
Why join us
- Impact: Help build the technical foundation for one of the most ambitious programs in reproductive biology
- Ownership: Take responsibility for difficult, high-value workflows and help make them reproducible and scalable
- Growth: Develop deep expertise in technically demanding reproductive and stem cell biology methods
- Community: Work alongside passionate scientists tackling one of the most exciting frontiers in biology with a deeply aligned team
- Mission: Build the biological foundation for a new era of reproductive medicine, expanding what is possible for millions of people and families with limited options today
Come and work with us
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, excellent healthcare benefits, and a collaborative research environment focused on meaningful results.
If you are passionate, hardworking, and aligned with our mission, we want to hear from you.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104 https://www.nature.com/articles/nature20104
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
Senior Scientist, RNA Delivery
Conception · Berkeley, California, USA
Pay
$120k–200k
Setting
On-site
Experience level: PhD or equivalent industry experience.
About Conception
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, RNA biology, and synthetic biology to make this vision a reality.
The position
We are seeking a highly creative, rigorous, and hands-on Scientist with deep expertise in RNA delivery to help optimize and enhance Conception’s differentiation platform.
This position sits at the intersection of RNA biology, delivery technology, stem cell differentiation, and platform development. You will be responsible for building robust, scalable, and biologically effective delivery workflows that enable us to test and deploy programs across multiple differentiation contexts.
What you’ll do
- Develop RNA delivery workflows for payload expression in different cell types and culture set ups. Apply RNA delivery strategies to improve and accelerate Conception’s differentiation platform.
- Optimize RNA format, delivery chemistry and formulation, dose, timing, repeat delivery, expression, viability, and biological activity.
- Build assays to measure delivery efficiency, target expression, and differentiation outcomes. Support screening workflows for RNA constructs, genes of interest, delivery conditions, and combinatorial perturbations.
- Collaborate across differentiation, cell engineering, and computational teams.
What we’re looking for
REQUIRED
- PhD or equivalent experience in RNA Biology, Cell Biology, Stem Cell Biology, Bioengineering, Synthetic Biology, Developmental Biology, or a related field.
- Hands-on experience delivering RNA into mammalian cells in various formats.
- Experience with most up to date RNA delivery technologies (LNPs, ligand conjugates, exosomes, electroporation, etc.) and standard readouts such as flow cytometry, imaging, qPCR, reporter assays, or RNA-seq.
- Experience delivering RNA or nanoparticles into complex culture systems.
- Experience optimizing delivery parameters such as dose, formulation, timing, repeat dosing, expression duration, toxicity, and biological effect.
- Strong experimental design, troubleshooting, documentation, and data interpretation skills.
PREFERRED
- Experience with iPSCs, ESCs, primary cells, differentiating cells, or other difficult-to-transfect cell types.
- Experience using RNA-based differentiation approaches.
- Experience with different RNA format design, production, purification, characterization, or delivery.
- Experience with medium- or high-throughput screens, ORF libraries, combinatorial perturbations, or barcoded workflows.
- Familiarity with scRNA-seq or related single-cell approaches.
- Familiarity with developmental biology, reproductive biology, germ cell development, ovarian biology, or organoid systems.
Come and work with us
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
Research Associate or Associate Scientist, Genome Engineer
Conception · Berkeley, California, USA
Pay
Not listed
Setting
On-site
Experience level: Masters, PhD or equivalent experience.
About Conception
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells. Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, and synthetic biology to make this vision a reality.
The position
- We are seeking a highly organized, rigorous, and hands-on Research Associate or Associate Scientist with strong experience in genome and cell engineering to help build tools that enhance Conception’s differentiation platform. In this role, you will generate engineered cell lines, including reporter lines, knock-out and knock-in lines, and overexpression lines to enable better tracking, control, and optimization of differentiation systems.
- This position sits at the intersection of genome engineering, stem cell biology, assay development, and differentiation platform development. You will be responsible for designing, building and validating robust engineered cell systems using CRISPR-based approaches, DNA-integrating expression systems, and constitutive or inducible transgene expression platforms. The ideal candidate has strong hands-on experience with mammalian cell engineering, tissue culture, careful clonal line generation, molecular validation, and expression tracking, and is excited to apply these tools to complex differentiation systems.
What you’ll do
- Build engineered cell lines to support Conception’s differentiation platform, including reporter lines, knock-out lines, knock-in lines, and overexpression lines.
- Use CRISPR-based genome engineering approaches to design, generate, screen, and validate edited cell lines.
- Develop DNA-integrating expression systems for constitutive and inducible transgene expression during differentiation.
- Optimize workflows for transfection, transduction, selection, clonal isolation, expansion, genotyping, and expression validation. Build assays to track reporter activity, transgene expression, silencing, differentiation state, and biological outcomes.
- Support differentiation experiments using engineered lines to monitor and improve cell fate transitions. Collaborate across differentiation, organoid, cell engineering, and computational teams.
What we’re looking for
REQUIRED
- Bachelor’s or Master’s degree in Cell Biology, Molecular Biology, Stem Cell Biology, Bioengineering, Genetics, Synthetic Biology, Developmental Biology, or a related field, or equivalent experience.
- Hands-on experience with mammalian cell culture and cell engineering workflows.
- Experience with CRISPR genome engineering, including knock-out, knock-in, or reporter line generation. Experience designing, generating, screening, and validating engineered cell lines using molecular and functional assays.
- Experience with DNA delivery or integrating expression systems such as plasmid transfection, viral transduction, PiggyBac, Sleeping Beauty, lentiviral systems, or related approaches.
- Experience with standard validation and readout assays such as PCR, genotyping, sequencing, flow cytometry, imaging, qPCR, reporter assays, or immunostaining.
- Strong experimental execution, troubleshooting, documentation, organization, and data interpretation skills.
PREFERRED
- Experience with iPSCs, ESCs, primary cells, differentiating cells.
- Experience building reporter lines to track gene expression, cell state, or differentiation.
- Experience with inducible expression systems, constitutive expression systems, promoter testing, or transgene expression optimization.
- Experience assessing or troubleshooting transgene silencing during extended culture or differentiation.
- Experience with CRISPRa, CRISPRi, dCas9-based systems, or other gene modulation approaches.
- Familiarity with stem cell differentiation, developmental biology, reproductive biology, germ cell development, ovarian biology, or organoid systems.
Come and work with us
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
(Senior) Scientist, Stem Cell
Conception · Berkeley, California, USA
Pay
$120k–200k
Setting
On-site
Experience level: PhD plus postdoctoral training or equivalent industry experience (typically 4+ years post-PhD for senior level).
About Conception
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, and reproductive biology to make this vision a reality.
The position
We are seeking an extremely hard-working, highly skilled, hands-on scientist or scientific specialist to support our pluripotent stem cell program. This is a technical specialist role for someone who wants to be in the lab doing difficult, delicate, high-impact work.
Ideally, you have direct experience deriving, establishing, expanding, banking, and characterizing pluripotent stem cell lines. We are looking for a rigorous bench scientist who is excited to execute, troubleshoot, repeat, improve, and master technically demanding workflows. The right person will be flexible in focus, willing to learn new techniques, and motivated to contribute wherever the lab needs them most. Experience with QC readout establishment, stem cell differentiation, 3D culture, or related reproductive biology techniques is highly valuable.
Title is negotiable based on experience and may range from Scientific Specialist to Senior Scientist.
What you’ll do
- Build, optimize, and repeatedly execute workflows needed for stem-cell-derived reproductive cell development
- Derive, establish, expand, bank, and characterize iPSC & ESC lines
- Maintain high-quality ESC/iPSC cultures, document passage history and culture conditions, and support characterization and QC assays
- Troubleshoot protocols, improve reproducibility, and help maintain consistency across difficult and delicate workflows
- Establish epigenetic quality readouts
- Collaborate closely with stem cell, reproductive biology, embryology, genomics, and preclinical teams
- Execute technically demanding workflows with precision, timing, repetition, and consistency
What we’re looking for
- PhD in stem cell biology, developmental biology, reproductive biology, cell biology, embryology, bioengineering, or a related field
- Ideally 4+ years of hands-on experience with human pluripotent stem cell culture, reproductive biology, or related technical workflows
- Direct experience with ESC/iPSC derivation, or ESC/iPSC line establishment is especially valuable
- Strong aseptic technique and experience maintaining sensitive, high-value cell lines
- Excellent attention to detail, reliability, and comfort with difficult, repetitive protocols that require precision and consistency
- Hands-on experience with ESC/iPSC expansion and banking, stem cell QC, 3D culture, organoid culture, co-culture systems, microdissection, micromanipulation, or long-duration tissue and cell culture workflows is highly desirable
- Strong work ethic and team-first mindset. Willing to do hands-on work, including routine and repetitive tasks, and step in wherever needed
- Able to thrive in a high-intensity, fast-paced, flexible startup environment
Why join us
- Impact: Help build the technical foundation for one of the most ambitious programs in reproductive biology
- Ownership: Take responsibility for difficult, high-value workflows and help make them reproducible and scalable
- Growth: Develop deep expertise in technically demanding reproductive and stem cell biology methods
- Community: Work alongside passionate scientists tackling one of the most exciting frontiers in biology with a deeply aligned team
- Mission: Build the biological foundation for a new era of reproductive medicine, expanding what is possible for millions of people and families with limited options today
Come and work with us
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, excellent healthcare benefits, and a collaborative research environment focused on meaningful results.
If you are passionate, hardworking, and aligned with our mission, we want to hear from you.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104 https://www.nature.com/articles/nature20104
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
Senior Scientist, Organoid
Conception · Berkeley, California, USA
Pay
$120k–200k
Setting
On-site
Senior Scientist, Organoid and Tissue Systems
Experience level: PhD plus postdoctoral training or equivalent industry experience (typically 3+ years post-PhD).
About Conception
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs).
Our work combines stem cell biology, cell engineering, developmental biology, tissue engineering, and computation to recreate the key stages of human ovarian development in the lab. We recently shared that we have, for the first time, generated early human egg cells and follicles entirely from stem cells https://www.conception.bio/science-and-updates/the-first-early-human-eggs-from-stem-cells. The next major challenge is to support those fully stem cell-derived follicles through growth and maturation.
We are building a world-class scientific team to solve this problem and create new possibilities for fertility and reproductive health.
The position
We are seeking an exceptionally strong, hands-on senior scientist to help drive the development of advanced 3D tissue and organoid systems.
The strongest candidates will have personally built new differentiation, organoid, or complex multicellular culture systems and worked through the biological and technical challenges required to improve their fidelity, maturation, function, and reproducibility.
Direct reproductive biology experience is not required. We are excited about scientists who have built difficult systems in other tissues and can bring new approaches to ovarian biology.
In this role, you will lead the development of advanced stem-cell-derived ovarian tissue systems central to Conception’s mission. You will work across developmental biology, cell-cell interactions, tissue organization, the cellular microenvironment, matrix and mechanics, signaling, metabolism, computation, and culture design to build systems that more faithfully recapitulate human ovarian biology.
What you’ll do
- Own the scientific strategy and day-to-day development of our ovarian organoid and follicle niche systems
- Design and build new differentiation and tissue engineering approaches that support follicle formation, growth, maturation, and oocyte competence
- Identify the main biological and technical bottlenecks, prioritize the highest-value experiments, and systematically improve the system
- Establish quantitative, stage-specific, and functional readouts that distinguish meaningful biological progress from marker expression alone
- Remain deeply hands-on and close to the cultures, experiments, and data
- Work closely with cross-functional teams to integrate complementary approaches and advance shared scientific goals
- Mentor and develop scientists while setting a high bar for rigor, documentation, pace, and scientific thinking
- Help build a team culture grounded in curiosity, urgency, flexibility, technical excellence, and transparency
What we will provide
You will build from a strong scientific foundation, including advanced stem-cell-derived ovarian tissue systems, extensive internal datasets, and human reference biology. You will work closely with a strong cross-functional team across stem cell biology, developmental biology, reproductive biology, computation, and engineering.
We will provide the resources and flexibility to test new approaches, bring in the right tools and collaborators, and build additional expertise around the program as it grows. You will have direct support from scientific and company leadership and meaningful ownership over the direction of the work.
What we’re looking for
- PhD in a relevant field, plus postdoctoral training or equivalent industry experience
- Strong track record of personally building or substantially improving complex organoid, tissue, or differentiation systems
- Deep understanding of cell-cell interactions and how the microenvironment shapes tissue development and function
- Exceptional hands-on troubleshooting and experimental judgment
- Ability to set scientific direction, prioritize clearly, and turn complex data into actionable next steps
- Clear communicator who is highly organized, keeps strong records, and works well across teams
- Strong work ethic and willingness to stay close to the bench, including routine work when needed
- Able to learn quickly and work effectively in a fast-moving startup environment
- Experience in reproductive biology, ovarian development, or germ cell biology is a plus
Why join us
- Impact: Own one of Conception’s most critical preclinical programs, with the potential to transform human reproduction
- Growth: Develop and lead a small team and expand scope as the program scales
- Community: Work alongside passionate scientists tackling one of the most exciting frontiers in biology with a deeply aligned team
- Mission: Build the biological foundation for a new era of reproductive medicine, expanding what is possible for millions of people and families with limited options today
Come and work with us
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104 https://www.nature.com/articles/nature20104
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
General Application
Conception · Berkeley, California, USA
Pay
$30k–85k
Setting
On-site
Help us make egg cells from stem cells
Listed by Conception for a position based in the United States. Employers on this board attest they are hiring domestically.
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