At Freenome, we are seeking a Senior Development Scientist I to help grow the Freenome Genomics Late Development team. You will develop, optimize, verify, and validate clinical-grade assay technologies for Freenome's multiomic platform, advancing our mission to detect cancer earlier. Working across manual and automated workflows, you will collaborate with cross-functional teams to develop and transfer robust NGS-based assays into a regulated, high-throughput production environment. You are passionate about developing life saving diagnostics using NGS technologies, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.
The role reports to the Senior Manager of Genomics Development. This role will be an onsite role based in our Brisbane, California headquarters.
What you’ll do:
Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approaches.
Oversee and lead mission-critical experiments to optimize, characterize, verify, and validate NGS-based assays, owning scientific strategy, experimental design, planning, timelines, execution, and delivery.
Design and execute high-impact experiments, generate detailed documentation, perform data analysis, create summary presentations, and present results cross-functionally.
Troubleshoot complex technical challenges, identify root causes, and drive process improvements to assay performance and laboratory workflows.
Drive project planning and prioritization by defining milestones, identifying and mitigating risks, and adapting to evolving program needs.
Build productive working relationships and partner cross-functionally with computational scientists, engineers, and clinical laboratory team members to transition development protocols into clinical production, including automation, validation experiments, and SOP development.
Document product development requirements and author study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP) to maintain high standard of scientific rigor and quality.
Must haves:
PhD in molecular biology, biochemistry, genetics, or a related field with at least 4 years of professional experience in the life sciences, or a Bachelors or Masters degree with at least 10 years of professional experience. Prior experience in clinical diagnostics and/or working in a start-up environment is preferred.
Experience designing and leading the execution of verification and validation studies for IVD assays in a regulated clinical laboratory environment (GLP).
Extensive hands-on experience in Next-gen sequencing (NGS) based automated assay development including extraction, library preparation, target capture, and sequencing. Experience working with automated platforms and liquid handlers.
Extensive hands-on experience in nucleic acid preparation, amplification, and quantification (DNA/RNA extraction and purification, PCR, qPCR, Qubit, Fragment Analyzer, Tapestation). Experience in working with ctDNA/cfDNA as an analyte in NGS workflows.
Proven track record of designing, planning, and executing successful experiments, including performing independent data analysis and giving effective scientific presentations.
High attention to detail and ability to record accurate and detailed observations, assess impact, and lead independent troubleshooting investigations.
Excellent written and verbal communication. Proactive communicator with ability to foster collaboration in a multidisciplinary team.
Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.
Experience providing technical mentorship and training to other scientists and research associates to contribute to a culture of technical excellence and continuous improvement.
Nice to haves:
Experience in working with with methylated ctDNA/cfDNA as an analyte in NGS workflows.
Familiarity with scientific programming or data analysis tools such as Python or R, and experience contributing to publications, patents, or other scientific innovations.
Benefits and additional information:
The US target range of our base salary rate for new hires is (Insert range here, low of Tier 3 and high of Tier 1). You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
At Freenome, we are seeking a Senior Research Associate to help grow the Freenome Genomic Early Development team. As a Senior Research Associate, you will participate in the development of genomic assay technologies and contribute to Freenome’s multiomic product portfolio aimed at early cancer detection. You will work closely with Scientists, Automation Engineers, and Computational Biologists to develop, optimize, and characterize efficient automated workflows to improve experimental and clinical throughput in a regulated high throughput environment. You will also work with Operations, Quality, and Regulatory to transfer complex methodologies, processes, and assays to Operations to ensure the highest quality data is produced by our clinical lab. You are passionate about contributing to developing life-saving diagnostics through early cancer detection, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.
The role reports to the Senior Manager of Genomic Early Development team. This role will be an Onsite role based in our Brisbane, California headquarters.
What you’ll do:
Apply hands-on knowledge of molecular biology, nucleic-acid biochemistry and next generation sequencing to develop and optimize NGS based methods and processes following principles of Design Controls for IVD development.
Design and perform experiments to develop, optimize, and characterize NGS workflow including DNA/RNA extraction, library preparation, target capture, and sequencing.
Operate and maintain NGS related instruments such as automated liquid handlers, PCR instruments, and sequencers.
Conduct new reagents testing and develop reagent quality control methods.
Participate in troubleshooting issues, identify and implement process improvement for the entire analytical workflow.
Collaborate with research, computational scientists, and automation engineers to transfer research prototype assays from Research to Development.
Collaborate with Quality Control Lab, Manufacturing lab, Quality, and Regulatory to transfer reagent quality control methods and manufacturing processes from Development to Operations and support the implementation of the methods and processes in Operations.
Accurately record results in electronic lab notebooks, author work instructions and record forms, contribute to writing study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP).
Must haves:
Bachelor’s in molecular biology, biochemistry, or a related field with at least 4 years of experience in the life sciences or Master’s in molecular biology or a related field.
Hands-on experience in Next-gen sequencing (NGS) based assay development including extraction, library preparation, target capture, and sequencing.
Familiarity with molecular biology, genomics, NGS, assay development, sample preparation, reagent handling, or related laboratory workflows (e.g. plasma separation processes, DNA/RNA extraction, purification, and quantification, NGS library preparation).
Experience designing, planning, and executing successful experiments, interpreting results, preparing data for review, and giving effective scientific presentations.
High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required.
Ability to manually pipette with high confidence, accuracy, and precision.
Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.
Strong organizational skills and the ability to contribute the design and implementation of new processes.
Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.
Nice to haves:
Experience in working with with methylated ctDNA/cfDNA as an analyte in liquid biopsy workflows.
Experience with automated liquid handlers, laboratory information systems, sample tracking systems, and equipment scheduling/status tools.
Familiarity with programing in a scientific programming language (e.g., Python or R).
Benefits and additional information:
The US target range of our base salary rate for new hires is $97,850 - $126,000. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Staff Computational Biologist
Remote
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About this opportunity:
At Freenome, we are seeking a Staff Computational Biologist to help grow the Freenome Computational Biology, Assay Research (CBAR) team. As part of our team, you will apply your scientific expertise to the development of early, noninvasive tests for cancer detection. With a strong background in NGS assay development, bioinformatics, statistics, and molecular biology, you will design and execute research studies to drive early research of prototype cancer early detection products using cfDNA as biomarker. You will work closely and cross-functionally with many teams, including Molecular Research and Development, Model R&D, and Computational Biology, Assay Development to enable the concept and feasibility of multiple molecular assays as part of Freenome’s diagnostic products.
The role reports to a Manager and Senior Staff Computational Biologist. This position can be a hybrid or fully remote role.
What you’ll do:
Lead the analysis and interpretation of molecular and clinical data in the context of early cancer detection, serving as a key thought leader on the Computational Science team.
Suggest research hypotheses and areas for potential computational model and assay improvement; then plan, scope, and execute associated research in partnership with a multidisciplinary team, owning projects from ideation through implementation.
Develop bioinformatics pipelines to enable high throughput NGS data processing and analysis.
In collaboration with wet lab scientists, rapidly characterize and iterate on experimental methods by providing real-time assessments of assay performance, quality control, and clinical/diagnostic utility.
Remain at the forefront of molecular techniques in oncology, and collaborate with the larger team to bring forward the next generation of assays for early cancer detection.
Must haves:
PhD degree in computational biology, cancer biology, statistics, bioinformatics, or related quantitative field.
6+ years of scientific industry experience applying computational techniques for biological discovery and product development, ideally to cancer or diagnostics applications in industry.
Extensive experience in NGS assay and pipeline development. Demonstrated track record of implementing complex workflows for high throughput NGS data processing.
Strong quantitative reasoning and data analysis skills, with a demonstrated ability to apply them effectively to relevant scientific problems.
Strong computational and programming skills, including thorough experience with Python statistical packages (Numpy, Matplotlib, Pandas) or equivalents in other languages like R.
Excellent oral and written communication skills to communicate to both scientific and broader audiences.
Ability to work on a cross-functional team in our highly collaborative environment, working with both computational and experimental scientists.
Nice to haves:
Expert knowledge of chromatin biology, liquid biopsy, DNA methylation and their relevance in cancer early detection.
Extensive experience working with DNA methylation data for biomarker discovery research.
Experience in developing, applying, and evaluating statistical and/or machine learning algorithms.
Benefits and additional information:
The US target range of our base salary rate for new hires is $188,275 - $270,375. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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Strategic Account Executive (South)
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About this opportunity:
Freenome is seeking a Strategic Account Executive (South) to help us redefine the landscape of early cancer detection by driving programmatic adoption of screening in health systems. The ideal candidate is proactive and driven and will be instrumental in adoption and implementation of Freenome’s early cancer detection tests, and digital health platform. The Strategic Account Executive will meet sales goals within the assigned geography by networking and building relationships with health systems and institutions. You will partner with the implementation team to ensure adoption of Freenome’s tests. The successful candidate will be assessed on quality and quantity of contracts in accordance with Freenome’s high performing standards.
The role will initially report to the Vice President of Sales. This role will be a Remote role within the South and will require the ability to travel 50% of working time away from work location, may include overnight/weekend travel.
What you’ll do:
Become a subject matter expert in Freenome’s technology and service offerings, effectively representing the company to key stakeholders including C-suite, executives, KOL physicians, Medical Directors, Hospital Administrators, Lab Directors, Precision Medicine Directors and Senior Management of Partner Labs
Be an amazing sales person, effectively articulating the value of Freenome’s industry leading tests and digital health tools to executive and provider leadership within health systems
Partner with Medical Affairs to educate and recruit Health Systems to utilize Freenome’s test
Negotiate and close contracts with health systems and institutions
Collaborate with both internal and external stakeholders in order to implement EMR and UX tools that will drive growth of Freenome’s test
Capture information on customer interactions using CRM tools, including point of contact information, sales call activities, market intelligence, funnel development, and other data points
Provide feedback to the Product and Marketing team directly from customers
Structure detailed strategic plans for gaining and retaining health systems and institution contracts
Identify market opportunities, monitor competitive activity, and present findings to commercial leadership
Must haves:
Bachelor’s Degree in Sales, Business Management, Marketing or, Science, or any other related field
10+ years of medical sales experience and 3+ years with a strong record of success selling complex diagnostics solutions to health systems or institutions
Experience with institutional sales successfully closing and implementing contracts with health systems
Understanding of the healthcare system, reimbursement pathways, and screening protocols
Strong communication, negotiation, and stakeholder engagement skills
Strong presentation skills: ability to effectively convey concepts in a clear, concise, and professional manner through telephone and face-to-face interactions
Experience with CRM tools and data-driven account planning
Ability to sell technically complex products
Possession of a valid driver's license
Nice to haves:
Experience with liquid biopsy early cancer detection
Demonstrated experience promoting digital health solutions to health systems
Experience selling disruptive technologies and improving the standard of care
Benefits and additional information:
The US target range of our base salary for new hires is $175,000 - $210,000. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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Vice President, Product Management
Brisbane, California
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About this opportunity:
The Vice President of Product Management will own the development and execution of Freenome’s product portfolio roadmap across three verticals: assay development, digital health, and the data platform. Working in close partnership with leaders across the company, this individual will translate clinical, scientific, customer, and business needs into a cohesive product strategy enabled by AI/agents that supports early cancer detection and patient access.
In assay development, this role will define product requirements and roadmap priorities for Freenome's diagnostic tests and test versioning through assay enhancements and AI. Across digital health, this leader will define the product experiences and workflows for patients, providers, and internal operations, with a focus on usability, access, and adoption. For the data platform, this role will lead defining capabilities, analytics, and data products needed to connect biological, clinical, and customer insights to portfolio decisions and product performance.
The role reports to the Chief Product Officer. As a member of the Senior Leadership Team, you will contribute to guiding and refining company-level strategy. Your commitment to patient care and access will significantly contribute to our growth and our mission to outpace cancer with early detection. This role will be a hybrid role based in our Brisbane, California headquarters.
What you’ll do:
Define, lead, develop, and implement the Freenome product roadmap with deep AI/agent integration and strategy in partnership with the Senior Leadership Team and Chief Product Officer that meets personalized care portfolio objectives.
Lead a team of product managers and technical product managers, inspiring the team with a clear vision and direction to enable excellence in execution, innovation, and collaboration.
Coach and develop a multi-disciplinary team, fostering a culture of continuous learning and growth.
Develop and implement comprehensive product strategies, including market analysis, product development, and lifecycle management.
Lead and influence through deep clinical and scientific market understanding to guide effective product portfolio and development priorities.
Own the overall product portfolio roadmap through organizational alignment of competing dynamics in science, commercial, regulatory, market access, clinical pathways, and patient preferences.
Own and lead decision making forums that prioritize and define R&D and product pipelines aligned with company strategy and objectives.
Drive product decisions and priorities using strategic frameworks and quantitative analyses.
Architects and integrates AI automation, agentic workflows and enablement strategies for Freenome’s product roadmap.
Establish and maintain relationships with key customers and partners, gathering feedback and insights to inform product development and improvement.
Monitor and analyze market trends, competitor activities, and customer feedback to identify opportunities for product innovation and enhancement.
Define and track key performance indicators (KPIs) for product performance and customer satisfaction, using data to drive decision-making and continuous improvement.
Represent the company at industry events, conferences, and in the media, serving as a thought leader in product management.
Must haves:
Bachelor's degree in Business, Marketing, Engineering, or a related field; Master's degree preferred.
Minimum of 15 years of progressive experience in product management; management consulting experience a plus.
Minimum of 10 years leadership experience building and cultivating high-performing teams.
Prior oncology, primary care, and consumer experience.
Prior in vitro diagnostic product launch experience.
Strong understanding of the diagnostics market, including regulatory and compliance landscape, competitive dynamics and customer and patient behavior.
Proven track record of developing and launching successful products in a competitive market.
Strong understanding of customer experience principles and methodologies, with experience leading customer-centric initiatives.
Excellent leadership and team-building skills, with the ability to inspire and motivate cross-functional teams.
Strong analytical and problem-solving skills, with a data-driven approach to decision-making.
Exceptional communication and interpersonal skills, with the ability to engage and influence stakeholders at all levels.
Willingness to travel as needed to meet with customers, partners, and teams.
Benefits and additional information:
The US target range of our base salary rate for new hires is $293,550 - $383,775. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
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Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.
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Research Associate I/II
Brisbane, California
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About this opportunity:
At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Associate I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. Starting with a prototype assay, you will contribute to developing and validating clinical-grade assays to measure complex, blood-based analytes. You will work closely with multiple teams including molecular research, computational science, automation engineering, and clinical operations to develop the assays in a regulated, high-throughput environment as well as identify ways to rapidly iterate and improve on existing methods to evaluate technologies that can enhance our end-to-end test performance.
The role reports to the Senior Manager and Staff Research Scientist. This role will be an Onsite role.
What you’ll do:
Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA.
Characterize automated assays by generating and analyzing experimental data.
Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments.
Collaborate with research team and computational biologists, understand how data reflect underlying molecular biology, and contribute to analyzing data and generating study conclusions.
Present data in cross functional teams.
Participate in troubleshooting efforts and design experiments with some supervisor guidance.
Help with process improvements across the lab by thinking critically about the execution of all experiments.
Must haves:
Bachelors with 1+ years of relevant industry experience or Masters in molecular biology, or a related field.
Hands-on experience in NGS based assay development including sample preparation, library preparation, target capture, and sequencing.
Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.
High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required.
Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.
Ability to manual pipette with high confidence, accuracy, and precision.
Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.
Nice to haves:
Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development).
Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers.
Experience using ELN (electronic lab notebook) and LIMS (lab information management system).
Familiarity with programing in a scientific programming language (e.g., Python or R).
Benefits and additional information:
The US target range of our base hourly rate for new hires is $37.68 - $46.69. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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Describe a hands-on NGS assay you’ve worked on from sample prep through sequencing. What parts you handled, what you learned, and how your work supported assay development?*
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Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.
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Senior Director, Real World Data (RWD)
Remote
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About this opportunity:
As the Senior Director of Real World Data (RWD), you will be accountable for defining, developing, and implementing our RWD strategy, platform, and data pipeline to transform diverse real-world datasets into regulatory-grade, research-ready assets that drive our clinical development, evidence generation, digital health products and product offerings. You will play a key role informing regulatory decisions, improving clinical trial efficiency, evaluating and implementing AI/agentic workflows to strengthen our RWD platform and help bridge the gap between clinical research and medical practice to improve patient outcomes and advance our vision of a world without disease.
The Senior Director will lead all informatics aspects of developing and maintaining a “regulatory-grade” RWD pipeline. Specifically, the Senior Director will lead the RWD Informatics team in turning electronic health records (EHR), claims, imaging, and other RWD sources into research-ready datasets accessible by our biostatisticians,computational scientists and other end users while ensuring data quality, operational efficiency, and scalability.
These efforts will contribute to developing and commercializing a portfolio of early cancer detection products — based on both clinical and multiomics data — and digital health solutions that will enable payers, providers, and patients to catch cancers early when curative intervention is most achievable.
The role reports to the Chief Product Officer. This role will be a Remote role.
What you’ll do:
Lead the operations and continuous improvement of our RWD curation pipeline, managing internal and external resources as needed. Evaluate and integrate agentic workflows and AI to ensure accuracy, augment the interpretability and quality, and drive efficiencies across our RWD efforts. This includes:
Designing and implementing processes, analytical methods, and AI tools to integrate a variety of RWD sources.
Preparing data for analysis, including data cleaning and mapping.
Ensuring “regulatory-grade” data quality where required.
Developing a scalable unstructured data curation operation, leveraging automation as much as possible and only transiently leveraging manual techniques with a roadmap towards eliminating these steps as appropriate.
Create a comprehensive, multi-year strategy for the acquisition, management, curation, and use of RWD to support regulatory submissions, clinical evidence generation, health economics and outcomes research (HEOR), and commercial efforts such as patient identification and care navigation.
Architect, build, and maintain a robust, efficient, and scalable RWD platform and pipeline capable of ingesting, linking, harmonizing, and curating large, complex, and disparate real-world datasets such as Electronic Health Records (EHRs), claims data, imaging, and registries of structured and unstructured data.
Lead clinical data analyses to support product strategy, development and commercialization to improve Freenome’s access to RWD and enhance future product offerings for HCOs.
Serve as the RWD expert, proactively collaborating with Clinical Development, Biostatistics, Regulatory Affairs, Medical Affairs, Engineering, Science and Product and Commercial teams to ensure the RWD pipeline meets diverse end-user needs, clinical, scientific and commercial objectives.
Contribute to defining the strategic direction of Freenome's data initiatives, in partnership with senior leadership and cross-functional teams.
Support data acquisition by conducting technical due diligence, facilitating data acquisition agreements and defining data delivery specifications and lead data product implementation efforts into Freenome’s platforms with strategic partners and customers.
Oversee the translation of raw RWD datasets into research-ready, regulatory-grade datasets, following OMOP or other industry-standard models, suitable for rigorous statistical analysis and real-world evidence (RWE) generation.
Foster a quality mindset through data quality checks, governance policies, and standard operating procedures (SOPs) to ensure the integrity, privacy, security, and traceability of all RWD assets to meet regulatory requirements.
Develop the team, building technical and leadership capabilities and coaching for high-performance proficiency.
Directly lead a team of clinical informaticists and data analysts through clear direction and priorities and hands-on management to enable focused execution in alignment with company objectives.
Manage the RWD department budget, ensuring efficient resource utilization and allocation of expenditures.
Build and maintain a culture of collaboration and inclusivity both within RWD and cross-functionally across Freenome.
Must haves:
Master’s or Ph.D. in Biostatistics, Epidemiology, Health Informatics, Computer Science, or a related quantitative field.
At least 12 years of progressive experience in clinical informatics, including experience with:
EHR, claims, other structured and unstructured RWD, and molecular data.
Applying RWD to device, therapeutic and/or software product development.
RWD across multiple disease areas, including oncology.
At least 10 years of experience building and leading high-performing, multi-disciplinary teams.
Demonstrated success operating within a matrixed organization and proactively collaborating with teams of internal and external partners to guide product delivery from concept to completion.
Passion for getting in the trenches, leading by example, and scaling technical platforms and teams.
Excellent written and verbal communicator with strong stakeholder management capabilities and problem-solving skills.
Experience leading data modeling, terminology normalization, data curation and/or unstructured data abstraction via natural language processing (NLP).
Deep knowledge of ontologies commonly used by health systems and payers (ICD-10, HCPCS, CPT, LOINC, RxNorm).
Experience with Python, R, and/or SQL.
Nice to haves:
Experience supporting real-world evidence FDA submissions or payer/guideline dossiers.
Clinical background (MD, NP, RN, or similar) and/or degree in health informatics.
Experience with cloud-based data storage and processing environments (e.g. AWS, Azure, GCP).
Experience working directly with health systems or data vendors on data licensing and ingestion projects.
Benefits and additional information:
The US target range of our base salary rate for new hires is $236,300 - $335,475. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.
As set forth in Freenome’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
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If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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Why are you being asked to complete this form?
We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:
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Listed by Freenome for a position based in the United States. Employers on this board attest they are hiring domestically.
Director, Evidence Generation and Publications
Remote
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About this opportunity:
Freenome is seeking a Director, Evidence Generation and Publications to lead integrated evidence-generation and publication strategies across the company’s portfolio.
This role will identify evidence gaps, develop research and analysis plans, and oversee the dissemination of clinical, real-world, economic, and operational data. The Director will partner across Scientific and Medical Affairs, Clinical Development, Biostatistics, Data Science, Regulatory Affairs and Market Access.
The ideal candidate is a strategic scientific leader with deep experience in evidence generation, publication planning, and cross-functional collaboration.
This role reports to the VP, Medical Affairs. This role will be a Remote role.
What you’ll do:
Evidence-generation strategy
Develop and execute integrated evidence plans aligned with clinical, regulatory, market-access, and commercial priorities.
Identify evidence gaps and translate them into readily executable research questions, study concepts, and analysis plans.
Lead post hoc analyses, real-world evidence and registry studies, and investigator-sponsored research.
Guide evidence development throughout the product lifecycle (feasibility, validation, and post-marketing studies).
Establish clear governance, prioritization, timelines, and measures of impact.
Publication and scientific-dissemination strategy
Develop and manage publication plans aligned with Freenome’s scientific communication strategy.
Oversee manuscripts, abstracts, posters, oral presentations, and other scientific materials.
Ensure timely, accurate, and compliant dissemination of data.
Partner with internal authors, external investigators, medical writers, statisticians, and third-party vendors.
Track publication progress and scientific impact.
Scientific leadership and cross-functional collaboration
Serve as a strategic partner across Science, Scientific and Medical Affairs, Clinical, Regulatory, Market Access, Commercial,, and Biometrics.
Translate complex findings into clear and credible scientific narratives.
Provide guidance on study design, endpoints, analyses, interpretation, and dissemination.
Align internal teams on evidence priorities, scientific messaging, and publication timing.
Present strategies and program updates to senior leadership.
External research and scientific engagement
Represent Freenome at scientific congresses, advisory boards, and research meetings.
Build relationships with investigators, academic institutions and healthcare systems.
Evaluate and support investigator-sponsored.
Identify external partnerships that strengthen Freenome’s evidence base.
Governance, quality, and compliance
Ensure adherence to applicable company policies, publication standards, and ethical guidelines, including GPP and ICMJE.
Maintain high standards for scientific integrity, authorship, transparency, and data accuracy.
Manage vendors, research partners, contracts, budgets, timelines, and program risks.
Must haves:
Advanced degree (MS or PhD) in medicine, science, public health, epidemiology, health economics, pharmacy, or a related field.
10+ years of relevant diagnostics, medical device, or healthcare experience, ideally in oncology.
Demonstrated experience leading evidence generation and publication strategies.
Strong knowledge of clinical research, real-world evidence, epidemiology, biostatistics, and scientific data interpretation.
Experience authoring and supervising manuscripts, abstracts, posters, and scientific presentations.
Proven ability to lead complex cross-functional initiatives in a matrixed organization.
Excellent written, verbal, presentation, and stakeholder-management skills.
Strong commitment to scientific integrity and compliant collaboration
Nice to haves:
Experience in oncology, cancer screening, molecular diagnostics, genomics, multiomics, or liquid biopsy.
Experience supporting diagnostic products, including screening tests, through their development, regulatory review, launch, and/or lifecycle management.
Experience with real-world data, health economics, implementation science, or healthcare delivery research.
Established relationships with investigators, academic institutions, or professional societies.
Prior people-management experience.
Benefits and additional information:
The US target range of our base salary rate for new hires is $214,625 - $305,550. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.
As set forth in Freenome’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
Gender
Select...
Are you Hispanic/Latino?
Select...
Race & Ethnicity Definitions
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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Expires 07/31/2029
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Listed by Freenome for a position based in the United States. Employers on this board attest they are hiring domestically.
Research Scientist I/II
Brisbane, California
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About this opportunity:
At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. As a Research Scientist in Genomics, you will contribute to the program’s technical base by creating and optimizing new next-generation sequencing (NGS) assays and workflows for DNA/RNA, or to the program’s scientific base by elevating our understanding of the biological context of these assay signals in cancer. In this role, you will perform studies to evaluate emergent technologies that have the potential to improve our diagnostic tests, and collect and analyze NGS datasets (including genomics, epigenomics, and transcriptomics) for biomarker discovery. You will also work closely with computational biologists and machine learning scientists to provide biological and technical insights, and to provide new data sources to enhance ongoing computational research projects.
The role reports to a Manager of Molecular Research. This role will be an Onsite role.
What you’ll do:
Independently design and execute experiments to help optimize the performance of Freenome’s new or existing assays.
Prototype new next-generation sequencing (NGS) methods, optimize the performance of existing assays, and execute biomarker discovery studies on clinical samples.
Assist with project planning and timeline generation and work with cross-functional teams to coordinate tasks within and across projects.
Take detailed notes, gather high-quality data, and openly communicate on lessons learned while performing experiments.
Independently troubleshoot workflows and understand the rationale behind workflow optimization choices.
Help with process improvements across the lab by thinking critically about the execution of all experiments.
Perform advanced analysis and data visualization of results to answer experimental questions and guide next steps.
Prepare and present experiment or project results at internal meetings, with clear articulation of goals, results, conclusions, and how results presented fit in to broader project.
Must haves:
PhD in molecular biology, biochemistry, genetics, or a related field or Bachelor’s or Master’s with 8+ years experience post-Bachelor’s in the life sciences (industry and/or academia).
Hands-on experience with and expert-level knowledge in NGS based workflows including sample preparation, library preparation, target capture, and sequencing.
Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.
Ability to perform advanced data analysis and critically examine experimental results.
Proven track record of designing and running successful experiments, preparing data for review, and giving effective scientific presentations.
Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.
Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.
Nice to haves:
Ability to perform bioinformatic analysis in a scientific programming language (e.g., Python or R).
Experience handling and preparing blood and/or tissue samples.
Experience running high-throughput experimental designs and/or assays on an automated liquid handling platform.
Experience using ELN (electronic lab notebook) and LIMS (lab information management system).
Benefits and additional information:
The US target range of our base salary rate for new hires is $132,050 - $167,475. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.
Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Applicants have rights under Federal Employment Laws.
Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)
California applicants please review the CCPA Notice at Collection here:
California Consumer Privacy Act (CCPA)
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Freenome’s mission relies heavily on optimizing and innovating next-generation sequencing (NGS) assays. Can you describe a specific instance where you independently designed an experiment to troubleshoot or optimize a complex NGS workflow (e.g., sample preparation, library preparation, or target capture)? What challenges did you face, and how did you critically evaluate the data to guide your next steps?*
In this role, you will work closely with computational biologists and machine learning scientists to provide biological insights for biomarker discovery. Tell us about a time you collaborated with computational teams or stakeholders in adjacent disciplines on a genomics dataset. How did you communicate your biological findings to guide the project? (Note: If you have experience using Python or R for your own bioinformatic analysis, please highlight how you utilized it in this project).*
A key aspect of this role is evaluating emergent technologies and understanding the biological context of assay signals in cancer. Briefly describe your hands-on expertise with human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology. How have you previously prototyped a new method or evaluated an emerging technology to improve biological detection or answer a challenging scientific question?*
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As set forth in Freenome’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
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Expires 07/31/2029
Why are you being asked to complete this form?
We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.
How do you know if you have a disability?
A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:
Alcohol or other substance use disorder (not currently using drugs illegally)
Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
Blind or low vision
Cancer (past or present)
Cardiovascular or heart disease
Celiac disease
Cerebral palsy
Deaf or serious difficulty hearing
Diabetes
Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
Epilepsy or other seizure disorder
Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
Intellectual or developmental disability
Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
Missing limbs or partially missing limbs
Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
Partial or complete paralysis (any cause)
Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
Short stature (dwarfism)
Traumatic brain injury
Disability Status
Select...
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
Submit application
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